RANGE OF RADIOCHEMICAL DAMAGE TO DNA WITH DECAY OF I125
RANGE OF RADIOCHEMICAL DAMAGE TO DNA WITH DECAY OF I125
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DOI：
10.1126/science.7256283
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发表时间：
1981-01-01
期刊：
影响因子：
56.9
通讯作者：
HASELTINE, WA
中科院分区：
文献类型：
--
作者：
MARTIN, RF;HASELTINE, WA
对125I标记脱氧胞苷衰变后产生的DNA片段长度的研究表明，大多数放射化学损伤发生在15-20 . ang范围内。125I衰变的位置然而，DNA链断裂可检测到70 . ang。从125I衰变的位置
Studies of the length of DNA fragments produced upon decay of 125I labeled deoxycytidine that was located at a single position within a DNA fragment of defined sequence demonstrate that most radiochemical damage occurs within 15-20 .ANG. of the site of 125I decay. However, DNA strand breakage was detectable up to 70 .ANG. from the site of 125I decay.