Prevalence of risk factors to coronary heart disease in an Arab-American population in Southeast Michigan
Prevalence of risk factors to coronary heart disease in an Arab-American population in Southeast Michigan
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DOI：
10.1080/09637480220138124
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发表时间：
2002-07-01
影响因子：
3.9
通讯作者：
Fungwe, TV
中科院分区：
文献类型：
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作者：
Hatahet, W;Khosla, P;Fungwe, TV
虽然在心血管疾病领域取得了重大进展，但很少有研究针对少数民族群体。居住在密歇根州东南部的阿拉伯裔美国人（AA）人口数量庞大且不断增长，他们患心血管疾病的风险可能正在增加。本研究的目的是评估一个拥有大量移民的AA社区中心血管疾病危险因素和相关行为因素的患病率，这些移民的生活方式发生了重大变化。居住在密歇根州东南部的352名AA成员，大部分来自中东，研究人员对他们进行了筛查，以确定他们的饮食和吸烟习惯、体重指数（BMI）、体脂分析、血压和完整的脂质分析。超重定义为BMI大于或等于第三次全国健康和营养检查调查（NHANES III）中年龄和性别特定参考数据的第85百分位值。相关分析用于检查与超重相关的因素，并对年龄和性别进行调整。血液胆固醇浓度与已公布的中东国家阿拉伯人的数据进行了比较。35岁及以上受试者超重的总体患病率显著高于NHANES III参考数据(男性，27.7%(95%可信区间，21.8-34.5)；女性，33.7%（95%可信区间，27.9-40.1）。在40岁以上的人群中，平均胆固醇浓度为210 +/- 4 mg/dl。男性和女性的平均高密度脂蛋白(HDL)-胆固醇水平分别为38和48毫克/分升。超过54.6%的受试者有总胆固醇：高密度脂蛋白比率bbbb4.5。尽管超重和肥胖在这一人群中很普遍，但男性的平均BMI为25.7 +/- 0.34，而女性为27 +/- 0.58。BMI升高与血压升高、血糖升高、总胆固醇升高、高密度脂蛋白胆固醇降低极显著相关（P < 0.01）。心血管疾病危险因素的升高在这一人群中普遍存在，这表明需要针对男性和女性肥胖的初级预防方案。这些结果可能部分归因于大多数移民人口典型的生活方式改变，表明患心血管疾病的风险增加。此外，本研究为今后干预改善这一人群的健康状况提供了依据。
Although significant advances have been made in the area of cardiovascular disease, few studies have targeted ethnic groups. There is a large and growing Arab-American (AA) population living in Southeast Michigan, whose risk of cardiovascular disease may be on the increase. The objective of this study was to evaluate the prevalence of cardiovascular disease risk factors and associated behavioral factors in an AA community with a large population of emigrants, subjected to significant lifestyle changes. Three hundred and fifty-two AA living in Southeast Michigan, mostly from the Middle East, were screened to determine their eating and smoking habits, body mass index (BMI) body fat analysis, blood pressure, and complete lipid profiling. Overweight was defined as a BMI greater than or equal to the 85th percentile value for age- and sex-specific reference data from the third National Health and Nutrition Examination Survey (NHANES III). Correlation analysis was used to examine factors associated with being overweight, with adjustment for age and sex. Blood cholesterol concentrations were compared with published data for Arabs from the Middle Eastern countries. The overall prevalence of being overweight in subjects aged 35 and older was significantly higher than NHANES III reference data (Men, 27.7% (95% confidence interval, 21.8-34.5); women, 33.7% (95% confidence interval, 27.9-40.1)). A mean cholesterol concentration of 210 +/- 4 mg/dl was observed in those over the age of 40. The mean high-density lipoprotein (HDL)-cholesterol levels for men and women were 38 and 48 mg/dl, respectively. Greater than 54.6% of all subjects had a total cholesterol: HDL ratio >4.5. Although being overweight and obesity were prevalent in this population, the mean BMI for men was 25.7 +/- 0.34, compared with 27 +/- 0.58 for women. Increased BMI was significantly correlated (P < 0.01) with increased blood pressure, increased glucose levels, increased total cholesterol and decreased HDL-cholesterol levels (P < 0.01). Elevation in risk factors to cardivoascular disease is prevalent in this population and indicates a need for programs targeting primary prevention of obesity in men and women. These results, which could be attributed in part to lifestyle changes typical of most emigrant populations, suggest an increase in the risk for developing cardiovascular disease. In addition, this study provides a basis for future intervention to improve the health of this population.