Abnormalities of somatosensory evoked potentials in spasmodic torticollis
Abnormalities of somatosensory evoked potentials in spasmodic torticollis
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痉挛性斜颈体感诱发电位异常
DOI：
10.1002/mds.870090408
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发表时间：
1994
影响因子：
8.6
通讯作者：
del Lavoro” Foundation Irccs
中科院分区：
文献类型：
--
作者：
L. Mazzini;M. Zaccala;C. Balzarini;“Ciinica;del Lavoro” Foundation Irccs
本研究检测了特发性痉挛性斜颈（ST）患者在3种不同刺激频率（1、3和6 Hz）下正中神经刺激的体感诱发电位（SEP）N20和N30波。将这些数据与从一组受帕金森病（PD）影响的患者和正常年龄匹配的受试者中收集的数据进行比较。与对照组相比，两组患者的N30振幅均显著降低。ST段降低幅度较大，N20波保持稳定。两种波的振幅都没有变化。当刺激率增加时，N30振幅显著降低，在患者和对照组中观察到类似的趋势。ST和PD中N30波的孤立异常支持涉及基底神经节或其与辅助运动区的连接的共同病理生理机制的假设。
This study examined the N20 and N30 waves of somatosensory evoked potentials (SEPs) from median nerve stimulation at three different stimulation rates (1, 3, and 6 Hz) in patients with idiopathic spasmodic torticollis (ST). The data were compared with those collected from a group of patients affected by Parkinson's disease (PD) and normal age‐matched subjects. N30 amplitude was significantly decreased in both groups of patients with respect to the controls. The decrease was larger in patients with ST. The N20 wave remained stable. The latencies of both waves were unchanged. When the stimulus rate was increased, the N30 amplitude decreased significantly, with a similar trend observed in both patients and controls. The isolated abnormalities of the N30 wave in both ST and PD support the hypothesis of a common physiopathogenetic mechanism that involves the basal ganglia or their connections with the supplementary motor area.