Linear chaining of etienic acid derivatives with the amide bond.: Synthesis of oligomeric steroids

Linear chaining of etienic acid derivatives with the amide bond.: Synthesis of oligomeric steroids
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DOI:
10.1135/cccc20010933
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发表时间:
2001-06-01
影响因子:
--
通讯作者:
Drasar, P
Drasar, P
中科院分区:
其他
文献类型:
--
作者:
Cerny, I;Budesínsky, M;Drasar, P

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Synthesis of linear molecules containing two to four steroid units connected with the amide bonds was developed. As a repeating unit, 3 beta -hydroxyandrost-5-ene-17 beta -carboxylic acid (etienic acid) was used. An active ester of this acid with N-hydroxysuccinimide and its 3-azido analogue were prepared-and methods for the preparation of higher oligomers were studied.