Green synthesis of Copper Oxide/Carbon nanocomposites using the leaf extract of Adhatoda vasica Nees, their characterization and antimicrobial activity
Green synthesis of Copper Oxide/Carbon nanocomposites using the leaf extract of Adhatoda vasica Nees, their characterization and antimicrobial activity
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DOI：
10.1016/j.heliyon.2020.e03323
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发表时间：
2020-02-01
期刊：
影响因子：
4
通讯作者：
Xavier, T. S.
中科院分区：
文献类型：
--
作者：
Bhavyasree, P. G.;Xavier, T. S.
使用 Adhatoda vasica 叶提取物在室温下通过绿色方法开发了氧化铜/碳（CuO/C）纳米复合材料。在这里，叶子提取物充当封端剂、还原剂和形成纳米复合材料的碳源。据我们所知，这是第一篇关于使用这种叶子提取物合成 CuO/C 纳米复合材料的文章。将五水硫酸铜溶液与植物提取物在一定条件下混合制备纳米复合材料。通过 XRD、UV-Visible、FTIR、FE SEM、EDS、XPS 和 TGA 对合成材料进行了表征。结果表明，合成的材料是氧化铜和功能化类石墨烯碳的复合材料。 SEM图像表明CuO/C纳米片的平均厚度为7-11 nm。此外，还检查了复合材料的抗真菌活性和抗菌活性。该纳米复合材料对致病性大肠杆菌、铜绿假单胞菌、肺炎克雷伯菌和金黄色葡萄球菌表现出显着的抗菌活性，对黑曲霉和白色念珠菌表现出显着的抗真菌活性。此外，还确定了纳米复合材料针对真菌白色念珠菌和细菌肺炎克雷伯菌的最低抑制浓度（MIC）和最低杀真菌/杀菌浓度（MFC/MBC）。
Copper Oxide/Carbon (CuO/C) nanocomposites were developed through the green method using the leaf extract of Adhatoda vasica at room temperature. Here, the leaf extract serves as a capping agent, reducing agent and a source of carbon for the formation of nanocomposites. As we know, this is the first article on the synthesis of CuO/C nanocomposites using this leaf extract. The nanocomposites were prepared by mixing the copper sulphate pentahydrate solution with the plant extract under certain conditions. The synthesized material was characterized by XRD, UV-Visible, FTIR, FE SEM, EDS, XPS and TGA. The results revealed that the synthesized material is a composite of copper oxide and functionalized graphene-like carbon. The SEM images indicated that the CuO/C nanoflakes had an average thickness of 7-11 nm. Further, the composites were examined for antifungal activity and antibacterial activity. The nanocomposites showed significant antibacterial activity against the pathogenic bacterial strains Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus and antifungal activity against the fungi Aspergillus niger and Candida albicans. Also, the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal/Bactericidal Concentration (MFC/MBC) of the nanocomposites were determined against the fungus C. albicans and the bacteria K. pneumonia.