SHORT-TERM ASSOCIATION BETWEEN AIR-POLLUTION AND EMERGENCY ROOM VISITS FOR ASTHMA IN BARCELONA
SHORT-TERM ASSOCIATION BETWEEN AIR-POLLUTION AND EMERGENCY ROOM VISITS FOR ASTHMA IN BARCELONA
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DOI：
10.1136/thx.50.10.1051
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发表时间：
1995-10-01
期刊：
影响因子：
10
通讯作者：
ANTO, JM
中科院分区：
文献类型：
--
作者：
CASTELLSAGUE, J;SUNYER, J;ANTO, JM
背景 - 几项研究评估了城市空气污染物与哮喘住院或急诊室就诊之间的关联，但结果不一致。本研究的目的是评估 1985-9 五年期间西班牙巴塞罗那黑烟、二氧化硫、二氧化氮和臭氧水平与成人哮喘急诊就诊次数之间的关系。方法 - 每天因哮喘急诊就诊的人数取自旨在研究巴塞罗那发生的哮喘爆发的呼吸系统紧急情况登记册。使用控制气象和时间相关变量的泊松回归模型分别评估夏季和冬季哮喘就诊与污染物水平之间的关联。结果-黑烟与夏季哮喘就诊相关，但与冬季无关。当日黑烟浓度增加 25 μg/m(3) 时，哮喘就诊的相对风险 (RR) 为 1.082（95% CI 1.011 至 1.157）。当前和前三天黑烟的平均水平导致更强的关联（RR = 1.114（95％CI 1.010至1.160）。此外，二氧化氮与夏季（RR = 1.045，95％CI 1.009至1.081）和冬季（RR = 1.056，95％CI 1.011至1.081）的哮喘就诊相关。 1.104）前一天的二氧化氮水平没有发现与二氧化硫或臭氧的相关性。结论 - 这项研究提供了颗粒物污染对哮喘影响的进一步证据，并表明二氧化氮可能在成人支气管哮喘的恶化中起作用。
Background - Several studies have assessed the association between urban air pollutants and hospital admissions or emergency room visits for asthma with inconsistent results. The objective of this study was to assess the relation between levels of black smoke, sulphur dioxide, nitrogen dioxide, and ozone and adult emergency room visits for asthma in Barcelona, Spain during the five year period 1985-9.Methods - The daily number of emergency room visits for asthma was obtained from a register of respiratory emergencies designed to study the asthma outbreaks occurring in Barcelona. The association between asthma visits and levels of pollutants was assessed separately for summers and winters with Poisson regression models controlling for meteorological and time related variables.Results - Black smoke was associated with asthma visits in summer but not in winter. The relative risk (RR) of asthma visits for a 25 mu g/m(3) increase of current day concentrations of black smoke was 1.082 (95% CI 1.011 to 1.157). The mean current and previous three day levels of black smoke led to a stronger association (RR=1.114 (95% CI 1.010 to 1.160). In addition, nitrogen dioxide was associated with asthma visits in both summer (RR= 1.045, 95% CI 1.009 to 1.081) and winter (RR = 1.056, 95% CI 1.011 to 1.104). These associations were slightly higher for the previous day's level of nitrogen dioxide. No associations were found for sulphur dioxide or for ozone.Conclusions - This study provides further evidence of the effect of particulate pollution on asthma, and it suggests that nitrogen dioxide may have a role in the exacerbation of bronchial asthma in adults.