Marital adjustment and interleukin-6 (IL-6).
Marital adjustment and interleukin-6 (IL-6).
复制标题
婚姻调整和白介素 6 (IL-6)。
DOI：
10.1037/a0026902
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Sbarra,DavidA
中科院分区：
文献类型：
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作者：
Whisman,MarkA;Sbarra,DavidA
在先前关于婚姻功能与各种健康结果相关的研究的基础上，我们评估了美国第二次基于人群的中年发展调查(MIDUS II)中年龄在35岁至84岁(N=415)的已婚成年人样本中婚姻适应与炎症标志物之间的关系。具体地说，我们分别评估了男性和女性婚姻适应的积极维度(即伴侣支持)和消极维度(即伴侣紧张)与白介素6(IL-6)之间的关联，以及这些关联是否受到年龄的影响。结果表明：(A)在男性中，婚姻适应与IL-6无关；(B)在女性中，年龄缓和了婚姻适应与IL-6之间的关系；(C)在年轻女性中，伴侣支持和伴侣紧张与IL-6相关；(D)在年轻女性中，伴侣支持而不是伴侣紧张与IL-6唯一相关。在控制人口统计变量、健康状况指标、健康行为、抑郁症状和感受到的压力时，年轻女性的婚姻适应与IL-6之间的关联显著。这些发现表明，IL-6可能是研究亲密关系中与健康相关的生物反应的有用生物标记物，尤其是年轻女性，当伴侣支持程度较低时，可能会表现出更多的炎症。
Building on prior research that marital functioning is associated with a variety of health outcomes, we evaluated the association between marital adjustment and a marker of inflammation in a sample of married adults between the ages of 35 and 84 years old (N= 415) from the second wave of the population-based Survey of Midlife Development in the United States (MIDUS II). Specifically, we evaluated associations between positive (ie, partner support) and negative (ie, partner strain) dimensions of marital adjustment and interleukin-6 (IL-6) separately for men and women, and whether these associations were moderated by age. Results indicated that (a) marital adjustment was not associated with IL-6 in men,(b) age moderated the association between marital adjustment and IL-6 in women,(c) partner support and partner strain were associated with IL-6 in younger women, and (d) partner support but not partner strain was uniquely associated with IL-6 in younger women. The associations between marital adjustment and IL-6 in younger women were significant when controlling for demographic variables, health status indicators, health behaviors, depressive symptoms, and perceived stress. These findings suggest that IL-6 may be a useful biomarker for studying health-relevant biological responses within intimate relationships, and that young women, in particular, may exhibit increased inflammation when partner support is low.