Synthesis and property studies of N‐carboxymethyl chitosan
Synthesis and property studies of N‐carboxymethyl chitosan
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DOI：
10.1002/app.32925
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发表时间：
2011-03
影响因子：
3
通讯作者：
Q. Song;Ze Zhang;Jiangang Gao;Chunmei Ding
中科院分区：
文献类型：
--
作者：
Q. Song;Ze Zhang;Jiangang Gao;Chunmei Ding
以壳聚糖为原料，用氯乙酸代替较昂贵的乙醛酸，在水中合成了n -羧甲基壳聚糖（N-CMC）。最佳反应温度为90℃，反应时间为4 h，氯乙酸与壳聚糖的比例为5:1 （w/w）。产品替代度超过1.32。采用XRD、FTIR、1H-NMR对n -羧甲基壳聚糖进行了表征，并测定了不同取代度N-CMC的水溶性和等电点。FTIR和1H-NMR数据证实取代反应发生在氨基上。©2010 Wiley期刊公司高分子学报，2011
N-carboxymethyl chitosans (N-CMC) were synthesized from chitosan in water with chloroacetic acid instead of comparatively expensive glyoxylic acid. The optimal reaction conditions were 90°C and 4 h with a ratio of chloroacetic acid to chitosan 5 : 1(w/w). The degree of substitution of product exceeded 1.32. The N-carboxymethyl chitosans were characterized by XRD, FTIR, 1H-NMR, and the water solubility and isoelectric point of N-CMC with different degrees of substitution were determined. FTIR and 1H-NMR data has confirmed that the substitution reaction occurred on the amino groups. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011