The effect of HIV, behavioural change, and STD syndromic management on STD epidemiology in sub-Saharan Africa: simulations of Uganda
The effect of HIV, behavioural change, and STD syndromic management on STD epidemiology in sub-Saharan Africa: simulations of Uganda
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DOI：
10.1136/sti.78.suppl_1.i55
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发表时间：
2002-04-01
影响因子：
3.6
通讯作者：
Habbema, JDF
中科院分区：
文献类型：
--
作者：
Korenromp, EL;Bakker, R;Habbema, JDF
对艾滋病病毒（HIV）疫情可能如何影响乌干达的性传播疾病（STD）流行病学，以及在疫情的不同阶段HIV将如何影响基于症状的性传播疾病治疗方案的有效性进行了评估。使用动态传播模型STDSIM来模拟HIV以及四种细菌性和一种病毒性性传播疾病的传播。利用来自乌干达拉凯农村地区和其他乌干达人群的人口统计学、行为学和流行病学数据对模型参数进行了量化。研究结果表明，严重的HIV疫情会显著改变性传播疾病的流行病学，尤其是在伴有行为反应的情况下。在制定针对严重HIV疫情下基于症状的性传播疾病管理政策时，应考虑生殖器溃疡的细菌病因可能减少的情况。
An assessment was made of how the HIV epidemic may have influenced sexually transmitted disease (STD) epidemiology in Uganda, and how HIV would affect the effectiveness of syndromic STD treatment programmes during different stages of the epidemic. The dynamic transmission model STDSIM was used to simulate the spread of HIV and four bacterial and one viral STD. Model parameters were quantified using demographic, behavioural, and epidemiological data from rural Rakai and other Ugandan populations. The findings suggest that severe HIV epidemics can markedly alter STD epidemiology, especially if accompanied by a behavioural response. Likely declines in bacterial causes of genital ulcers should be considered in defining policies on syndromic STD management in severe HIV epidemics.