Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia

Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia
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DOI:
10.1248/cpb.52.1483
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发表时间:
2004-12-01
影响因子:
1.7
通讯作者:
Sha, Y
Sha, Y
中科院分区:
医学4区
文献类型:
--
作者:
Sun, K;Li, X;Sha, Y

文献摘要

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从播娘蒿(Descurainia sophia(L.)韦布·普兰托化合物4和5的结构经1D、2D NMR和HR-MS确证。
Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4-8), were isolated from the seeds of Descurainia sophia (L.) Webb ex Prantl. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity.