Two-dimensional blood flow vector and wall shear stress of carotid artery obtained with dual-angle Doppler method
Two-dimensional blood flow vector and wall shear stress of carotid artery obtained with dual-angle Doppler method
复制标题
双角度多普勒法获得颈动脉二维血流矢量及管壁剪应力
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Y. Saijo
中科院分区：
文献类型：
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作者：
Osamu Akagawa;Kosuke Fukazu;Ryo Nagaoka;Y. Saijo
动脉粥样硬化的生物力学评价主要通过生物医学超声中的组织定征和动脉壁弹性测量来研究。另一方面，动脉上的流体切应力也被认为是改变血管内皮特性导致动脉粥样硬化的重要因素。超声是一种合适的成像方式，以高时间分辨率测量血流。然而，传统的多普勒方法仅测量沿超声束沿着的速度分量。在本研究中，在颈动脉的二维血流矢量测量的双角度多普勒测量和验证的方法进行比较，粒子图像测速。此外，通过颈动脉中的流量分布来计算壁剪切应力。该研究有助于以非侵入性方式了解动脉粥样硬化的病理生理学。
Biomechanical assessment of atherosclerosis has been mainly studied by tissue characterization and elasticity measurement of arterial wall in biomedical ultrasound. On the other hand, fluid shear stress on the artery is also known as an important factor to change vascular endothelium properties leading to atherosclerosis. Ultrasound is a suitable imaging modality to measure blood flow with high temporal resolution. However, conventional Doppler method merely measures the velocity component along the ultrasonic beam. In the present study, two-dimensional blood flow vectors in carotid artery are measured by dual-angle Doppler measurement and validation of the method is performed in comparison with particle image velocimetry. Further, wall shear stress is calculated by flow distribution in the carotid artery. The study contributes to understand the pathophysiology of atherosclerosis in a non-invasive manner.
影响因子：
33.6
作者：
Chiu JJ;Chien S
通讯作者：
Chien S