Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis
Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis
复制标题
DOI：
10.1016/j.ijcard.2012.04.105
复制
发表时间：
2013-08-20
影响因子：
3.5
通讯作者：
Francis, Darrel P.
中科院分区：
文献类型：
--
作者：
Finegold, Judith A.;Manisty, Charlotte H.;Francis, Darrel P.
背景：目前尚不清楚哪种超声心动图测量方法最适合于真实世界主动脉瓣狭窄（AS）随访的系列测量。我们确定在真实的生活中，使用速度-时间-积分（VTI）或峰值速度（V-peak）测量主动脉瓣和左心室流出道速度之间的无量纲指数（DI）是否更一致。方法：对AS受试者6个月内获得的系列超声心动图进行盲法分析，比较使用V-peak计算的DI随时间的变化，使用VTI计算的DI。结果：配对超声心动图，平均间隔72天，从70例患者的AS严重程度（59%严重）进行了分析。使用V峰或VTI计算的DI在这段短时间内没有显著变化。当使用V峰计算DI时，变异系数明显优于VTI（12.6%对25.4%，p
Background: It remains unclear which echocardiographic measure is most suitable for serial measurement in real-world aortic stenosis (AS) follow-up. We determine whether the dimensionless index (DI) between aortic valve and left ventricular outflow tract velocities is measured more consistently using velocity-time-integral (VTI) or peak velocities (V-peak) in real life.Methods: Serial echocardiograms acquired within 6 months in subjects with AS were analysed with blinding, to compare the variability over time of DI calculated using V-peak, with that of DI calculated using VTI.Results: Paired echocardiograms, acquired on average 72 days apart, were analysed from 70 patients with a range of severities of AS (59% severe). DI, calculated using either V-peak or VTI, did not significantly change over this short time. Coefficient of variation was significantly better when DI was calculated using V-peak than VTI (12.6 versus 25.4%, p