CIRCULATING TRANSFERRIN RECEPTOR IN HUMAN-SERUM
CIRCULATING TRANSFERRIN RECEPTOR IN HUMAN-SERUM
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DOI：
10.1111/j.1365-2141.1986.tb04120.x
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发表时间：
1986-10-01
影响因子：
6.5
通讯作者：
URUSHIZAKI, I
中科院分区：
文献类型：
--
作者：
KOHGO, Y;NISHISATO, T;URUSHIZAKI, I
用灵敏的免疫分析方法在人血清中检测到循环转铁蛋白受体。健康男性和女性血清转铁蛋白受体的平均浓度为251。+-。94(平均值+-SD)ng/ml和256.+-。99 ng/ml。急性白血病、多发性骨髓瘤和恶性淋巴瘤患者的血清受体浓度变化很大，从正常到1100 ng/ml，经聚丙烯酰胺凝胶电泳法和免疫印迹分析，得到一条分子量在8万~10万道尔顿之间的单一条带。
Circulating transferrin receptor has been detected in human serum with a sensitive immunoassay. The mean concentrations of the serum transferrin receptor in healthy males and females were 251 .+-. 94 (mean .+-. SD) ng/ml and 256 .+-. 99 ng/ml, respectively. The serum receptor concentration in patients with haematological malignancies, including acute leukaemia, mutliply myeloma and malignant lymphoma, varied widely, from normal to 1100 ng/ml. A single band with an approximate molecular weight between 80,000 and 100,000 daltons was obtained by polyacrylamide gel electrophoresis-immunoblotting analysis of serum.