Changes in Cytomegalovirus Seroprevalence in Korea for 21 Years: a Single Center Study
Changes in Cytomegalovirus Seroprevalence in Korea for 21 Years: a Single Center Study
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DOI：
10.14776/piv.2018.25.e8
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发表时间：
2018-01-01
影响因子：
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通讯作者：
Kim, Yae-Jean
中科院分区：
文献类型：
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作者：
Choi, Sae Rom;KyungRanKim;Kim, Yae-Jean
目的：巨细胞病毒(CMV)感染大多无症状，但对某些宿主是有害的。我们调查了2000年前后韩国人巨细胞病毒血清阳性率的变化。方法：我们回顾了1995年1月至2015年12月在韩国首尔三星医疗中心接受CMV免疫球蛋白G(IgG)检测的患者的实验室数据。血清阳性率的变化按性别、年龄、地区和测试年份(第1期，1995-2005年与第2期，2006-2015年)进行分析。结果：CMV血清总阳性率为94.1%(10,900/11,584)。巨细胞病毒血清阳性率分别为94.2%和94.1%，两组间差异无统计学意义(P=0.862)。11~20岁年龄组第2期巨细胞病毒阳性率(78.8%)明显低于第1期(89.9%)(P=0.001)。31~40岁组血清阳性率(97.4%)显著高于年轻组(P
Purpose: Cytomegalovirus (CMV) infection is mostly asymptomatic but can be detrimental to certain hosts. We investigated changes of CMV seroprevalence in Koreans before and after the year 2000. Methods: We reviewed laboratory values of patients who were tested for CMV immunoglobulin G (IgG) at Samsung Medical Center, Seoul, Korea, from January 1995 to December 2015. Changes in seroprevalence were analyzed by gender, age, region, and tested year period (period 1, 1995–2005 vs. period 2, 2006–2015). Results: Overall CMV seropositivity was 94.1% (10,900/11,584). There was no significant difference for CMV seropositivity among the two periods (94.2% vs. 94.1%) ( P =0.862). CMV seropositivity in the 11 to 20-year age group in period 2 (78.8%) was significantly lower than that of period 1 (89.9%) ( P =0.001). The seropositivity of individuals aged 31–40 years (97.4%) was significantly higher than that of younger age groups ( P