Bacterial adherence to extended wear soft contact lenses.
Bacterial adherence to extended wear soft contact lenses.
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DOI：
10.1016/s0161-6420(90)32596-4
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发表时间：
1990-03
期刊：
影响因子：
13.7
通讯作者：
M. Aswad;T. John;M. Barza;K. Kenyon;J. Baum
中科院分区：
文献类型：
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作者：
M. Aswad;T. John;M. Barza;K. Kenyon;J. Baum
作者用放射性标记技术和电子显微镜研究了铜绿假单胞菌和金黄色葡萄球菌对有和无焦点沉积物的长戴型软性接触镜（EWSCL）的粘附性。相反，S. Aureus在体外没有显示出对接触透镜的显著粘附（即，放射性摄取不显著高于背景）。假单胞菌的粘附程度与晶状体上的病灶沉积物数量成正比。电子显微镜检查结果显示细菌主要粘附在大的局灶性沉积物（≥ 150 μm）上。小的局灶性沉积物（≤ 50 μm）上无假单胞菌粘附，局灶性沉积物之间的区域几乎无粘附。作者假设配戴的镜片，特别是那些有大量病灶沉积物的镜片，是P的运输工具。aerodynamosato角膜。这一假说可以部分解释肺炎链球菌引起的角膜炎的高发病率。EWSCL患者的气道狭窄。
The authors studied the adherence ofPseudomonas aeruginosaandStaphylococcus aureusto extended wear soft contact lenses (EWSCLs) with and without focal deposits using both a radiolabeling technique and electron microscopy.P. aeruginosashowed significant adherence to contact lenses in vitro. In contrast,S. aureusfailed to show significant adherence to contact lenses in vitro (i.e., the radioactive uptake was not significantly above background). The extent of adherence ofPseudomonaswas proportional to the number of focal deposits on the lenses. Results of electron microscopic examination showed the bacteria to be adherent primarily to large focal deposits (≥ 150 μm). There was no pseudomonal adherence to the small focal deposits (≤ 50 μm) and little adherence to the areas in between the focal deposits. The authors hypothesize that worn lenses, especially those with large focal deposits, serve as a vehicle for the transport ofP. aeruginosato the cornea. This hypothesis could be a partial explanation for the high incidence of keratitis caused byP. aeruginosain EWSCL patients.