Population-based risks of mortality and preterm morbidity by gestational age and birth weight
Population-based risks of mortality and preterm morbidity by gestational age and birth weight
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DOI：
10.1038/jp.2016.118
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发表时间：
2016-11-01
影响因子：
2.9
通讯作者：
Jelliffe-Pawlowski, L. L.
中科院分区：
文献类型：
--
作者：
Baer, R. J.;Rogers, E. E.;Jelliffe-Pawlowski, L. L.
目的：本研究的目的是检查小或大胎龄（SGA/LGA）状态对死亡率和发病率的影响，研究设计：采用逻辑二项回归计算SGA或LGA与适当生长（阿加）分娩按胎龄分层的婴儿死亡率和早产率的相对危险度（RR）和95%置信区间。与相似胎龄的阿加婴儿相比，SGA婴儿的婴儿死亡风险增加。出生于25 - 27周的LGA婴儿死亡风险降低（RR：0.6），但出生于28 - 31周的LGA婴儿死亡风险增加（RR：1.9）。早产发病率的风险增加了28和38周之间出生的SGA婴儿，但减少LGA婴儿出生前37 wk.CONCLUSION：这项研究表明，考虑胎龄出生体重的重要性时，评估发病率和死亡率的风险。
OBJECTIVE: The objective of this study is to examine the effect of small or large for gestational age (SGA/LGA) status on mortality and morbidity by gestational age.STUDY DESIGN: Logistic binomial regression was used to calculate relative risks (RRs) and 95% confidence intervals for infant mortality and preterm morbidities for SGA or LGA compared with appropriately grown (AGA) deliveries stratified by gestational age group.RESULTS: Compared with AGA infants of similar gestational age, SGA infants were at increased risk for infant mortality. Mortality risk was decreased for LGA infants born between 25 and 27 weeks (RR: 0.6) but increased for LGA infants born between 28 and 31 weeks (RR: 1.9). Risk of preterm morbidity was increased for SGA infants born between 28 and 38 weeks, but decreased for LGA infants born before 37 weeks.CONCLUSION: This study demonstrates the importance of considering birth weight for gestational age when evaluating morbidity and mortality risks.