Topographic organization of eye-position dependent gain fields in human visual cortex.

Topographic organization of eye-position dependent gain fields in human visual cortex.
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人类视觉皮层中依赖眼睛的增益场的地形组织。

DOI:
10.1038/s41467-022-35488-8
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发表时间:
2022-12-24
影响因子:
16.6
通讯作者:
Fracasso, Alessio
Fracasso, Alessio
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Fabius, Jasper H.;Moravkova, Katarina;Fracasso, Alessio

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The ability to move has introduced animals with the problem of sensory ambiguity: the position of an external stimulus could change over time because the stimulus moved, or because the animal moved its receptors. This ambiguity can be resolved with a change in neural response gain as a function of receptor orientation. Here, we developed an encoding model to capture gain modulation of visual responses in high field (7 T) fMRI data. We characterized population eye-position dependent gain fields (pEGF). The information contained in the pEGFs allowed us to reconstruct eye positions over time across the visual hierarchy. We discovered a systematic distribution of pEGF centers: pEGF centers shift from contra- to ipsilateral following pRF eccentricity. Such a topographical organization suggests that signals beyond pure retinotopy are accessible early in the visual hierarchy, providing the potential to solve sensory ambiguity and optimize sensory processing information for functionally relevant behavior. It is not fully understood how sensory ambiguity introduced by eye movements is resolved by the visual system. Here, the authors use an encoding model to capture gain modulation of visual responses in 7 T fMRI data.
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