In vivo MRI cell tracking: clinical studies.
In vivo MRI cell tracking: clinical studies.
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DOI：
10.2214/ajr.09.3107
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发表时间：
2009-08
期刊：
影响因子：
--
通讯作者：
Bulte JW
中科院分区：
文献类型：
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作者：
Bulte JW
这篇综述的目的是描述超顺磁性氧化铁MRI细胞追踪的原理和已经进行的四项临床试验。一旦干细胞疗法成为主流，临床MRI细胞追踪很可能成为床边的重要工具。这项技术最突出的作用可能是通过MRI引导注射验证准确的细胞输送，介入放射科医生将在不久的将来发挥作用。本文所述的所有临床研究均在美国境外进行。
The purpose of this review is to describe the principles of MRI cell tracking with superparamagnetic iron oxides and the four clinical trials that have been performed. Clinical MRI cell tracking is likely to become an important tool at the bedside once (stem) cell therapy becomes mainstream. The most prominent role of this technique probably will be verification of accurate cell delivery with MRI-guided injection, in which interventional radiologists will play a role in the near future. All clinical studies described as of this writing have been performed outside the United States.