Evolution of organellar proton-ATPases.
Evolution of organellar proton-ATPases.
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DOI：
10.1016/0005-2728(92)90072-a
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发表时间：
1992-05
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影响因子：
--
通讯作者：
N. Nelson
中科院分区：
文献类型：
--
作者：
N. Nelson
在每一个已知的活细胞中，质子ATPase都在生物能量转换中发挥作用。它们的无处不在和古老使它们成为进化研究的主要来源。有两个相关的H+-ATPase家族：F-ATPase家族在真细菌叶绿体和线粒体中起作用，而V-ATPase家族在真核细菌和真核细胞的空泡系统中存在。对V-和F-ATPase几个亚基的序列分析揭示了它们进化过程中的几个重要步骤。此外，这些研究揭示了真核生物各种细胞器的进化，并提出了真细菌、考古细菌和真核生物三界进化中的一些事件。
Proton ATPases function in biological energy conversion in every known living cell. Their ubiquity and antiquity make them a prime source for evolutionary studies. There are two related families of H+-ATPases; while the family of F-ATPases function in eubacteria chloroplasts and mitochondria, the family of V-ATPases are present in archaebacteria and the vacuolar system of eukaryotic cells. Sequence analysis of several subunits of V- and F-ATPases revealed several of the important steps in their evolution. Moreover, these studies shed light on the evolution of the various organelles of eukaryotes and suggested some events in the evolution of the three kingdoms of eubacteria, archaebacteria and eukaryotes.