Trends in corneal graft surgery in the UK
Trends in corneal graft surgery in the UK
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DOI：
10.1136/bjo.2010.182329
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发表时间：
2011-04-01
影响因子：
4.1
通讯作者：
Goldacre, Michael J.
中科院分区：
文献类型：
--
作者：
Keenan, Tiarnan D. L.;Carley, Fiona;Goldacre, Michael J.
目的-本研究的目的是检查趋势随着时间的推移和区域变化率的角膜移植手术在UK.Methods的医院住院病人查询（HIPE）和医院事件的统计（HES）进行了分析，角膜移植术在英格兰的招生从1971年至2006年。分析1999 - 2009年英国国民健康服务系统（NHS）血液和移植（NHSBT）角膜移植术的数据。结果HIPE和HES下的穿透性角膜移植（PK）年发生率从1971年的0.7/10万增加到1992年的3.9/10万，然后下降到2006年的3.1/10万。板层角膜移植术（LK）的发生率从0.1（1971年）增加到0.9（2006年）。NHSBT下的年度PK操作从1 901（1999/2000）减少到1 473（2008/2009）。在同一时期，深前板层角膜移植手术从每年91例增加到327例，而内皮角膜移植手术从每年2例增加到569例。地理分析显示，在1998 e2004年左右，角膜移植率在地方当局地区的变化很大，特别是对于LK.Conclusion角膜移植手术在英国进行的总数在过去十年中缓慢增加。板层角膜移植术与穿透性角膜移植术的比例有所增加，在英国各地的专科中心，LK的手术率最高。
Aims The aims of this study were to examine trends over time and regional variation in rates of corneal graft surgery in the UK.Methods The hospital in-patient enquiry (HIPE) and hospital episode statistics (HES) were analysed for keratoplasty admissions in England from 1971 to 2006. NHS Blood and Transplant (NHSBT) data were analysed for keratoplasty operations in the UK from 1999 to 2009.Results Annual rates of penetrating keratoplasty (PK) under HIPE and HES increased from 0.7 per 100 000 population (1971) to 3.9 (1992), then decreased to 3.1 (2006). Rates of lamellar keratoplasty (LK) increased from 0.1 (1971) to 0.9 (2006). Annual PK operations under NHSBT decreased from 1901 (1999/00) to 1473 (2008/9). Over the same period, deep anterior lamellar keratoplasty operations increased from 91 to 327 per year, while endothelial keratoplasty operations increased from 2 to 569 per year. Geographical analysis showed a wide variation across local authority areas in rates of keratoplasty around 1998e2004, especially for LK.Conclusion The total number of corneal graft operations performed in the UK has increased slowly over the past decade. The proportion of lamellar versus penetrating keratoplasty has increased, with LK performed at the highest rates in specialist centres distributed across the UK.