A community-based motivational personalised lifestyle intervention to reduce BMI in obese adolescents: results from the Healthy Eating and Lifestyle Programme (HELP) randomised controlled trial.
A community-based motivational personalised lifestyle intervention to reduce BMI in obese adolescents: results from the Healthy Eating and Lifestyle Programme (HELP) randomised controlled trial.
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DOI：
10.1136/archdischild-2016-311586
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发表时间：
2017-08
影响因子：
5.2
通讯作者：
Viner RM
中科院分区：
文献类型：
--
作者：
Christie D;Hudson LD;Kinra S;Wong ICK;Nazareth I;Cole TJ;Sovio U;Gregson J;Kessel AS;Mathiot A;Morris S;Panca M;Costa S;Holt R;Viner RM
在英国，大约7%的5-15岁的儿童和年轻人的肥胖水平可能与合并症有关。大多数多元生活方式方案对英国青少年的适用性和普适性有限。健康饮食和生活方式方案(HELP)是一项专门针对青少年的干预措施，专为寻求帮助控制体重的12至18岁肥胖儿童设计。参与者被随机分为12个疗程的HELP干预或标准护理。主要结果是26周时两组的平均体重指数(BMI)(kg/m2)的差异，调整了基线BMI、年龄和性别。174名受试者被随机分组(每组87人)，其中145人(83%)在第26周提供了主要结果数据。在第26周，干预对体重指数无显著影响(干预组平均体重指数变化0.18 kg/m2，对照组平均变化0.25 kg/m2；调整后的组间差值：−0.11 kg/m2(95% CI−0.62至0.40)，p=0.7)。在26周和52周时，两组之间在任何次要结果上都没有显著差异。至少，这项研究强调了更高水平、更有条理的干预措施的必要性，以应对英国和国际上日益增长的肥胖公共健康负担。在社区肥胖青少年样本中，HELP干预并不比单一的教育会议更有效地减少BMI。还需要进一步的工作，以了解如何有效地向来自不同贫困背景的年轻人提供体重管理方案，在这些背景下，儿童肥胖症很常见。这项研究在为公共卫生干预措施提供信息以解决儿童肥胖方面具有重要意义。ISRCTN：ISRCTN99840111。
Approximately 7% of children and young people aged 5–15 years in the UK have obesity at a level likely to be associated with comorbidities. The majority of multicomponent lifestyle programmes have limited applicability and generalisability for British adolescents. The Healthy Eating and Lifestyle Programme (HELP) was a specific adolescent-focused intervention, designed for obese 12 to 18-year-olds seeking help to manage their weight. Participants were randomised to the 12-session HELP intervention or standard care. The primary outcome was difference in mean body mass index (BMI) (kg/m2) between groups at week 26 adjusted for baseline BMI, age and sex. 174 subjects were randomised (87 in each arm), of whom 145 (83%) provided primary outcome data at week 26. At week 26 there were no significant effects of the intervention on BMI (mean change in BMI 0.18 kg/m2 for the intervention arm, 0.25 kg/m2 for the control arm; adjusted difference between groups: −0.11 kg/m2 (95% CI −0.62 to 0.40), p=0.7). At weeks 26 and 52 there were no significant differences between groups in any secondary outcomes. At minimum this study reinforces the need for higher level, structured interventions to tackle the growing public health burden of obesity in the UK and internationally. The HELP intervention was no more effective than a single educational session for reducing BMI in a community sample of obese adolescents. Further work is needed to understand how weight management programmes can be delivered effectively to young people from diverse and deprived backgrounds in which childhood obesity is common. The study has significant implications in terms of informing public health interventions to tackle childhood obesity. ISRCTN: ISRCTN99840111.
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影响因子：
3.4
作者：
Madson, MB;Campbell, TC;Melchert, TP
通讯作者：
Melchert, TP
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.9778/cmajo.20140047
发表时间：
2015-01-01
期刊：
CMAJ open
影响因子：
--
作者：
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通讯作者：
Raina, Parminder