Development of healthcare chips checking life-style-related diseases

Development of healthcare chips checking life-style-related diseases
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DOI：
10.1016/j.msec.2004.08.032
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发表时间：
2004-12-01
期刊：
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
影响因子：
--
通讯作者：
Horiike, Y
Horiike, Y
中科院分区：
其他
文献类型：
--
作者：
Oki, A;Ogawa, H;Horiike, Y

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我们研究了提供家庭医疗诊断的生物芯片，作为微型分析系统的应用。作为目标，开发了一种使用无痛针的电子血液采集系统。保健芯片和肝功能检测芯片都是在引入从微量血液中分离的血浆的基础上进行的。前者用电化学方法测定pH、Na+、K+、葡萄糖和BUN，后者用比色法测定γ-GTP、GOT和GPT。血液在微通道中的流动受离心力的控制。这些芯片对检查与生活方式有关的疾病很有用。(C)2004年，爱思唯尔出版。
We investigated biochips that provide a home medical diagnosis as an application of miniaturized analysis systems. As the objective, an electronic blood collection system employing a painless needle was developed. Both the healthcare chip and hepatic function examining chip were studied based on the introduction of plasmas separated from a trace amount of blood. The former electrochemically measures pH, Na+, K+, glucose and BUN, and the latter measures the gamma-GTP, GOT and GPT using a colorimetric analysis. The fluids of the blood in the micro-channel were controlled by centrifugal force. These chips are useful for checking life-style-related diseases. (C) 2004 Published by Elsevier B.V.