Prevalence and associated factors of oligohydramnios in pregnancies beyond 36 weeks of gestation at a tertiary hospital in southwestern Uganda.
Prevalence and associated factors of oligohydramnios in pregnancies beyond 36 weeks of gestation at a tertiary hospital in southwestern Uganda.
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DOI：
10.1186/s12884-022-04939-x
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发表时间：
2022-08-02
影响因子：
3.1
通讯作者：
中科院分区：
文献类型：
--
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羊水过少与不良的母亲和围产儿结局有关。在包括乌干达在内的低资源国家，由于缺乏超声检查服务，羊水过少未被发现。我们在乌干达西南部的姆巴拉拉地区转诊医院(MRRH)确定了怀孕超过36周的妇女羊水过少的患病率及其相关因素。我们从2019年11月到2020年3月进行了一项以医院为基础的横断面研究。其中包括胎龄为36周的 >； 的女性。被排除在外的是胎膜破裂的妇女、正在分娩的妇女和多胎妊娠的妇女。采访者管理的结构化问卷被用来获取研究参与者的人口统计学、产科和临床特征。我们使用超声扫描获得的羊水指数(AFI)来确定羊水过少。羊水过少的参与者被诊断为羊水过少， ≤ 为5 cm。我们进行了多变量Logistic回归以确定与羊水过少相关的因素。我们招募了426名女性，平均年龄27岁(SD ± 5.3)。在426名参与者中，有40人羊水过少，患病率为9.4%(95%可信区间：6.8-12.6%)。与羊水过少显著相关的因素是孕期疟疾史(AOR = 4.6；95%CI：1.5-14，P = 0.008)、初孕(AOR = 3.7；95%CI：1.6-6.7，P = 0.002)和孕龄增加；与37-39周、40-41周(AOR = 2.5；95%CI：1.1-5.6，P = 0.022)和 >的孕妇相比； 41周(AOR = 6.0；95%CI：2.3-16，P = 0.001)发生羊水过少的可能性较大。在寻求MRRH治疗的妇女中，大约每十人中就有一人被检测到羊水过少，这在初产妇、有孕期疟疾病史的人和过期妊娠的人中更为常见。我们建议加强对妊娠晚期羊水过少的监测，特别是对初级孕妇、有疟疾孕期病史的孕妇和过期妊娠的孕妇，以便能够迅速发现这种并发症并计划及时干预。未来的纵向研究需要评估在我们的环境中羊水过少的妇女的临床结果。
Oligohydramnios is associated with poor maternal and perinatal outcomes. In low-resource countries, including Uganda, oligohydramnios is under-detected due to the scarcity of ultrasonographic services. We determined the prevalence and associated factors of oligohydramnios among women with pregnancies beyond 36 weeks of gestation at Mbarara Regional Referral Hospital (MRRH) in Southwestern Uganda. We conducted a hospital-based cross-sectional study from November 2019 to March 2020. Included were women at gestational age > 36 weeks. Excluded were women with ruptured membranes, those in active labour, and those with multiple pregnancies. An interviewer-administered structured questionnaire was used to capture demographic, obstetric, and clinical characteristics of the study participants. We determined oligohydramnios using an amniotic fluid index (AFI) obtained using an ultrasound scan. Oligohydramnios was diagnosed in participants with AFI ≤ 5 cm. We performed multivariable logistic regression to determine factors associated with oligohydramnios. We enrolled 426 women with a mean age of 27 (SD ± 5.3) years. Of the 426 participants, 40 had oligohydramnios, for a prevalence of 9.4% (95%CI: 6.8–12.6%). Factors found to be significantly associated with oligohydramnios were history of malaria in pregnancy (aOR = 4.6; 95%CI: 1.5–14, P = 0.008), primegravidity (aOR = 3.7; 95%CI: 1.6–6.7, P = 0.002) and increasing gestational age; compared to women at 37–39 weeks, those at 40–41 weeks (aOR = 2.5; 95%CI: 1.1–5.6, P = 0.022), and those at > 41 weeks (aOR = 6.0; 95%CI: 2.3–16, P = 0.001) were more likely to have oligohydramnios. Oligohydramnios was detected in approximately one out of every ten women seeking care at MRRH, and it was more common among primigravidae, those with a history of malaria in pregnancy, and those with post-term pregnancies. We recommend increased surveillance for oligohydramnios in the third trimester, especially among prime gravidas, those with history of malaria in pregnancy, and those with post-term pregnancies, in order to enable prompt detection of this complication and plan timely interventions. Future longitudinal studies are needed to assess clinical outcomes in women with oligohydramnios in our setting.
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影响因子：
3.1
作者：
Byamukama O;Migisha R;Kalyebara PK;Tibaijuka L;Lugobe HM;Ngonzi J;Ahabwe OM;Garcia KRM;Mugyenyi GR;Boatin AA;Muhumuza J;Ssalongo WGM;Kayondo M;Kanyesigye H
通讯作者：
Kanyesigye H
DOI：
10.1016/0002-9378(95)90276-7
发表时间：
1995-08-01
影响因子：
9.8
作者：
BARHAVA, I;DIVON, MY;BARNHARD, Y
通讯作者：
BARNHARD, Y
DOI：
10.4314/jmbs.v4i3.1
发表时间：
2015-01-01
期刊：
JOURNAL OF MEDICAL AND BIOMEDICAL SCIENCE
影响因子：
--
作者：
Ogunlaja, O. A.;Fawole, A. A.;Idowu, A.
通讯作者：
Idowu, A.
DOI：
10.1080/14767058.2018.1553944
发表时间：
2020-07-01
期刊：
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
影响因子：
--
作者：
Hou, Lei;Wang, Xin;Zhang, Weiyuan
通讯作者：
Zhang, Weiyuan
DOI：
10.1371/journal.pgph.0000014
发表时间：
2021-12-07
期刊：
PLOS global public health
影响因子：
--
作者：
Alegana VA;Macharia PM;Muchiri S;Mumo E;Oyugi E;Kamau A;Chacky F;Thawer S;Molteni F;Rutazanna D;Maiteki-Sebuguzi C;Gonahasa S;Noor AM;Snow RW
通讯作者：
Snow RW