The relationship between normal lung sounds, age, and gender
The relationship between normal lung sounds, age, and gender
复制标题
DOI：
10.1164/ajrccm.162.3.9905104
复制
发表时间：
2000-09-01
影响因子：
24.7
通讯作者：
von Wichert, P
中科院分区：
文献类型：
--
作者：
Gross, V;Dittmar, A;von Wichert, P
听诊是检测肺部疾病最重要的无创且可行的方法之一。随着年龄的增长，呼吸音的系统性变化具有诊断意义。为了研究这些变化，我们记录了 162 名受试者后胸腔四个位置的肺音以及气流。根据年龄、性别和吸烟习惯对数据进行分析。为了描述肺音的功率谱，我们计算了平均频率和中值频率、具有最高功率的频率以及330至600Hz和60至330Hz这两个频带的相对功率的比率(Q)。使用线性回归分析来衡量这些变量的年龄依赖性。男性与女性之间存在 4 项显着差异（p < 0.05），但吸烟者与非吸烟者之间没有显着差异。在各组内，Q 和年龄之间存在较小但显着的相关性（r(2) 小于或等于 0.1，p < 0.05）。对于男性和女性来说，随着年龄的增长，330 至 600 Hz 频段的相对功率略有增加。然而，在个体差异较大的基础上，这些微小的变化（Delta Q接近5%，SD(Q)大于或等于+/-5%）没有临床意义，在通过分析肺音自动检测肺部疾病时不需要考虑。
Auscultation is one of the most important noninvasive and feasible methods for the detection of lung diseases. Systematic changes in breathing sounds with increasing age are of diagnostic importance. To investigate these changes, we recorded lung sounds taken from four locations in the posterior thorax of 162 subjects, together with airflow. The data were analyzed according to age, sex, and smoking habit. In order to describe the power spectrum of the lung sounds, we calculated mean and median frequency, frequency with the highest power, and a ratio (Q) of relative power of the two frequency bands of 330 to 600 Hz and 60 to 330 Hz. Linear regression analysis was used as a measurement of age-dependence of these variables. Significant differences in 4 were found in men versus women (p < 0.05), but not in smokers versus nonsmokers. Within the groups, a small but significant correlation existed between Q and age (r(2) less than or equal to 0.1, p < 0.05). For both men and women, a slight increase of the relative power In the frequency band of 330 to 600 Hz was recorded with increasing age. However, on the basis of large individual variations, these small changes (Delta Q similar to 5%, SD(Q) greater than or equal to +/- 5%) have no clinical significance and need not to be considered in the automatic detection of lung diseases by analyzing lung sounds.