Regional blood flow capillary permeability, and compartmental volumes: Measurement with dynamic CT - Initial experience
Regional blood flow capillary permeability, and compartmental volumes: Measurement with dynamic CT - Initial experience
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DOI：
10.1148/radiology.210.1.r99ja46269
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发表时间：
1999-01-01
期刊：
影响因子：
19.7
通讯作者：
Schreiber, W
中科院分区：
文献类型：
--
作者：
Brix, G;Bahner, ML;Schreiber, W
颈部肿瘤患者在给予对比剂后进行序贯计算机断层扫描。为了进行数据分析，采用了药代动力学双室，同时考虑了毛细血管血供和造影剂在毛细血管壁上的双向扩散。这种方法提供了定量表征组织微循环的可能性，包括区域血流、毛细血管通透性和相对隔室容积。
Sequential computed tomographic scanning was performed in patients with neck tumors after contrast material administration. For data analysis,a pharmacokinetic two-compartment was employed that takes into account both capillary blood supply and bidirectional diffusion of the contrast agent across the capillary wall. This approach offers the possibility to quantitatively characterize tissue microcirculation with regional blood flow, capillary permeability, and relative compartmental volumes.