Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA
复制标题
DOI：
10.1039/b412522c
复制
发表时间：
2005-01-01
影响因子：
4.9
通讯作者：
Ly, DH
中科院分区：
文献类型：
--
作者：
Dragulescu-Andrasi, A;Zhou, P;Ly, DH
具有 D 型主链结构和交替间隔的胍基肽核酸 (GPNA) 能够序列特异性地与 RNA 结合，并且很容易被人类体细胞和胚胎干 (ES) 细胞摄取。
Guanidine-based peptide nucleic acid (GPNA) with a D-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.