Preanalytical Delay Reduces Sensitivity of QuantiFERON-TB Gold In-Tube Assay for Detection of Latent Tuberculosis Infection
Preanalytical Delay Reduces Sensitivity of QuantiFERON-TB Gold In-Tube Assay for Detection of Latent Tuberculosis Infection
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DOI：
10.1128/jcm.01136-11
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发表时间：
2011-08-01
影响因子：
9.4
通讯作者：
Banaei, Niaz
中科院分区：
文献类型：
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作者：
Doberne, David;Gaur, Rajiv L.;Banaei, Niaz
测定了孵育延迟对量子结核金试管分析(QFT-GIT)准确度的影响。与即刻孵育相比，延迟6小时和12小时的阳性转阴率分别为19%(5/26)和22%(5/23)。这些发现强调了标准化QFT-GIT分析前实践的必要性。
The effects of incubation delays on the accuracy of the QuantiFERON-TB gold in-tube assay (QFT-GIT) were measured. Compared to immediate incubation, 6- and 12-hour delays resulted in positive-to-negative reversion rates of 19% (5/26) and 22% (5/23), respectively. These findings underscore the need for standardizing QFT-GIT preanalytical practices.