Nutritional influences on bone mineral density: A cross-sectional study in premenopausal women
Nutritional influences on bone mineral density: A cross-sectional study in premenopausal women
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DOI：
10.1093/ajcn/65.6.1831
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发表时间：
1997-06-01
影响因子：
7.1
通讯作者：
Reid, DM
中科院分区：
文献类型：
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作者：
New, SA;BoltonSmith, C;Reid, DM
对994名45-49岁健康绝经前妇女进行了膳食调查。采用双能X线骨密度仪（DXA）测量骨密度。饮食摄入量进行了评估与食物频率问卷（FFQ）。将能量调整后的营养摄入量分为四分位数，并计算腰椎（LS）、股骨颈（FN）、股骨转子（FT）和股骨Wards（FW）的平均BMD。随着锌、镁、钾和纤维摄入量的增加，LS BMD显著增加（P < 0.05-0.006），且这些营养素和维生素C摄入量的最低和最高四分位数之间LS BMD也存在显著差异（P < 0.05-0.01）。这些结果在调整重要的混杂因素后仍然具有显著性。报告在成年早期牛奶和水果摄入量低的妇女LS BMD和FT BMD低于中等或高摄入量的妇女（P < 0.01）。长期大量摄入这些营养素可能对骨骼健康很重要，可能是因为它们对酸碱平衡有有益的影响。
The association between current and past dietary intake and bone mineral density (BMD) was investigated in 994 healthy premenopausal women aged 45-49 y. BMD was measured with dual-energy X-ray absorptiometry (DXA). Dietary intake was assessed with a food-frequency questionnaire (FFQ). Energy-adjusted nutrient intakes were grouped into quartiles and mean BMD at the lumbar spine (LS), femoral neck (FN), femoral trochanter (FT), and femoral Wards (FW) were calculated. With higher intakes of zinc, magnesium, potassium, and fiber, LS BMD was significantly higher (P < 0.05-0.006), and a significant difference in LS BMD was also found between the lowest and highest quartiles for these nutrients and vitamin C intake (P < 0.05-0.01). These results remained significant after adjustment for important confounding factors. LS BMD and FT BMD were lower in women reporting a low intake of milk and fruit in early adulthood than in women with a medium or high intake (P < 0.01). High, long-term intakes of these nutrients may be important to bone health, possibly because of their beneficial effect on acid-base balance.