Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada's disease
Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada's disease
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DOI：
10.1016/j.ajo.2005.01.046
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发表时间：
2005-06-01
影响因子：
4.2
通讯作者：
Ohno, S
中科院分区：
文献类型：
--
作者：
Kitamura, M;Takami, K;Ohno, S
目的：Vogt-小柳-原田氏(Vogt-Koyanagi-Harada‘s，VKH)疾病委员会于2001年建立了“VKH疾病修订诊断标准”。本研究的目的是评估这些标准与传统的Sugiura诊断系统之间的一致性。设计：观察性病例系列。方法：对北海道大学医院葡萄膜炎调查门诊1991-2003年间根据Sugiura标准确诊的VKH患者的病历资料，采用VKH委员会修订的VKH疾病诊断标准进行回顾性分析。所有患者都是日本人，95例(56%)是女性。首次就诊时的平均年龄为44.7±13.9岁(9~74岁)。使用VKH委员会的新标准，91.7%的先前诊断的VKH患者被归类为患有这种疾病。其中11.8%为完全性VKH，71%为不完全性VKH，8.9%为疑似VKH。结论：VKH委员会修订的诊断标准对VKH的诊断有帮助，两种诊断标准的符合率均在90%以上。然而，由于VKH委员会的新标准排除了VKH病，以前做过白内障手术或没有浆液性视网膜脱离迹象的患者没有被归类为VKH病。(C)2005，Elsevier Inc.保留所有权利。
PURPOSE: The Vogt-Koyanagi-Harada's (VKH) Dis- ease Committee established the "Revised diagnostic criteria for VKH disease" in 2001. The purpose of the present study was to assess the concordance between these criteria and the traditional Sugiura's diagnosis system. DESIGN: Observational case series.METHODS: The medical records of patients previously diagnosed with VKH disease based upon Sugiura's criteria at the Uveitis Survey Clinic of the Hokkaido University Hospital between 1991 and 2003 were retrospectively reevaluated using the VKH Committee's revised diagnostic criteria for VKH disease.RESULTS: Sugiura's criteria were used to identify 169 patients with VKH disease. All patients were Japanese, and 95 cases (56%) were women. Mean age at the time of their first visit to our clinic was 44.7 +/- 13.9 years (range, 9 to 74 years). Using the VKH Committee's new criteria, 91.7% of the previously diagnosed VKH patients were classified as having the disease. Of this group, 11.8% were classified as complete, 71% incomplete, and 8.9% as probable VKH disease.CONCLUSIONS: The VKH Committee's revised diagnostic criteria proved useful for VKH disease diagnosis, as the concordance rate for the two criteria was more than 90%. However, patients who had prior cataract surgery or who lacked signs of serous retinal detachment were not classified as having VKH disease because of exclusion by the VKH Committee's new criteria. (c) 2005 by Elsevier Inc. All rights reserved.