Effects of cilostazol on platelet function.
Effects of cilostazol on platelet function.
复制标题
西洛他唑对血小板功能的影响。
DOI：
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复制
发表时间：
1989
期刊：
影响因子：
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通讯作者：
A. Hirayama
中科院分区：
文献类型：
--
作者：
S. Uehara;A. Hirayama
The antiplatelet effect of cilostazol (OPC-13013) was investigated by means of both in vitro and in vivo examinations. With the in vitro tests, cilostazol showed an inhibitive effect approximately 10 times greater than trapidil as a result of comparative examinations of the platelet aggregation inhibitive effect using trapidil as the control. In the in vivo tests, which were conducted to observe the platelet aggregation inhibitive effect as a result of oral administration of cilostazol at 100 mg/d for 4 weeks to patients with stable cerebral vascular diseases, a significant decrease in aggregation was recognized.
