Genetic data provided by 21 autosomal STR loci from Chinese Tujia ethnic group
Genetic data provided by 21 autosomal STR loci from Chinese Tujia ethnic group
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中国土家族21个常染色体STR基因座提供的遗传数据
DOI：
10.1007/s11033-012-1903-6
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发表时间：
2012-12-01
影响因子：
2.8
通讯作者：
Zhu, Bofeng
中科院分区：
文献类型：
--
作者：
Yuan, Guo-lian;Shen, Chun-mei;Zhu, Bofeng
本研究的目的是调查107名湖北土家族人群常染色体短串联重复序列（STR）基因座的等位基因频率分布和法医学遗传学参数。21个常染色体STR遗传标记（D9S1122、D6S474、D6S1017、D5S2500、D4S2408、D3S4529、D2S441、D2S1776、D22S1045、D20S482、D1S1677、D1S1627、D1GATA 113、D19S433、D18S853、D17S1301、D11S4463、D12ATA 63，D10 S1248、D10 S1435和D14 S1434）在一种新的多重聚合酶链反应系统中同时扩增。在土家族群体中共检测到155个等位基因，等位基因频率在0.005 ~ 0.589之间。21个STR基因座在土家族群体中的期望杂合度为0.579 ~ 0.824，多态信息含量为0.525 ~ 0.802，区分力为0.773 ~ 0.945，排除力为0.257 ~ 0.641。我们的研究结果表明，常染色体STR多重系统提供了高度信息的STR数据，并可能是有用的，在该地区的法医学个人识别和亲子鉴定。
The aim of this study was to investigate allelic frequency distribution and forensic genetic parameters of autosomal short tandem repeats (STR) loci of the population samples from 107 Tujia individuals from Chinese Hubei Province. Twenty-one autosomal STR genetic markers (D9S1122, D6S474, D6S1017, D5S2500, D4S2408, D3S4529, D2S441, D2S1776, D22S1045, D20S482, D1S1677, D1S1627, D1GATA113, D19S433, D18S853, D17S1301, D11S4463, D12ATA63, D10S1248, D10S1435 and D14S1434) were simultaneously amplified in a new multiplex polymerase chain reaction system. 155 alleles for all the STR loci from the Tujia population were observed and the corresponding allelic frequencies ranged from 0.005 to 0.589. Expected heterozygosity, polymorphic information content, power of discrimination and power of exclusion of the 21 STR loci in the Tujia population were from 0.579 to 0.824, from 0.525 to 0.802, from 0.773 to 0.945 and from 0.257 to 0.641, respectively. Our results indicate that the autosomal STRs multiplex system provides highly informative STR data and could be useful in forensic individual identification and parentage testing in this region.