Prediction of progression, from atypical to definite Meniere's disease using electrocochleography and glycerol and furosemide tests
Prediction of progression, from atypical to definite Meniere's disease using electrocochleography and glycerol and furosemide tests
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DOI：
10.1080/0036554021000028079
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发表时间：
2003-01-01
影响因子：
1.4
通讯作者：
Watanabe, Y
中科院分区：
文献类型：
--
作者：
Kimura, H;Aso, S;Watanabe, Y
为探讨耳蜗电图（ECochG）和甘油及速尿试验能否预测梅尼埃病（MD）从非典型进展到确诊，对1569例各种耳蜗前庭疾病患者进行了ECochG和甘油及速尿试验，包括确诊的MD、非典型MD、梅毒性中耳炎、迟发性内淋巴积水、突发性耳聋、耳蜗前庭病和感音神经性听力损失。非典型MD患者被分为五类，根据他们的symptoms.Results-A的115/118例（97%），明确MD谁接受了所有3个测试显示至少在I测试阳性结果。99例不符合明确MD诊断标准但在首次访视时有眩晕和/或听力损失的患者随后进展为明确MD。回顾性发现，92%的患者在初始阶段在这3项试验中至少显示1项阳性结果。在这些患者中，无论是ECochG或甘油试验呈阴性的测试结果，进展到明确的MD的可能性是low.Conclusion-The组合ECochG和甘油和速尿试验是有助于诊断内淋巴积水（ELH）。ECochG和甘油试验是预测非典型MD、突发性听力损失和其他耳蜗前庭疾病患者进展为明确MD的有效工具。我们的检测结果还表明，非典型MD的病理状态包括非ELH和ELH。
Objective-To investigate whether electrocochleography (ECochG) and glycerol and furosemide tests could predict progression from atypical to definite Meniere's disease (MD).Material and methods-ECochG and glycerol and furosemide tests were performed in 1569 patients with various cochleovestibular diseases, including definite MD, atypical MD, syphilitic labyrinthitis, delayed endolymphatic hydrops, sudden hearing loss, cochleovestibulopathy and sensorineural hearing loss. Patients with atypical MD were divided into five categories based on their symptoms.Results-A total of 115/118 patients (97%) with definite MD who underwent all 3 tests showed a positive result in at least I test. Ninety-nine patients who did not satisfy the diagnostic criteria of definite MD but had vertigo and/or hearing loss at the first visit subsequently progressed to definite MD. It was retrospectively found that 92% of patients showed at least 1 positive finding in these 3 tests at the initial stage. In those patients who showed a negative test result in either ECochG or the glycerol test, the possibility of progression to definite MD was low.Conclusion-The combination of ECochG and the glycerol and furosemide tests was helpful in diagnosing endolymphatic hydrops (ELH). ECochG and the glycerol test were effective tools for predicting the progression to definite MD in patients with atypical MD, sudden hearing loss and other cochleovestibular diseases. Our test results also indicated that the pathological state of atypical MD included both non-ELH and ELH.