Diminished forearm vasomotor response to central hypervolemic loading in aerobically fit individuals.

Diminished forearm vasomotor response to central hypervolemic loading in aerobically fit individuals.
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有氧运动个体对中心高容量负荷的前臂血管舒缩反应减弱。

DOI:
10.1097/00005768-199611000-00007
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发表时间:
1996
影响因子:
4.1
通讯作者:
Raven,PB
Raven,PB
中科院分区:
医学2区
文献类型:
--
作者:
Shi,X;Gallagher,KM;SMith,SA;Bryant,KH;Raven,PB

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The aim of this study was to test the hypothesis that cardiopulmonary baroreflex control of forearm vascular resistance (FVR) during central hypervolemic loading was less sensitive in exercise trained high fit individuals (HF) compared to untrained average fit individuals (AF). Eight AF (age: 24+/-1 yr and weight: 78.9+/-1.7 kg) and eight HF (22+/-1 yr 79.5+/-2.4 kg) voluntarily participated in the investigation. Maximal aerobic power (determined on a treadmill), plasma volume and blood volume (Evans blue dilution method) were significantly greater in the HF than AF (60.8+/-0.7 vs. 41.2+/-1.9 ml. kg-1. min-1, 3.96+/-0.17 vs 3.36+/-0.08 1, and 6.33+/-0.23 vs 5.28+/-0.13 1). Baseline heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP, measured by an intraradial catheter or a Finapres finger cuff), forearm blood flow (FBF, plethysmography), and FVR, calculated from the ratio (MAP-CVP)/FBF, were not different between the HF and the AF. Lower body negative pressure (LBNP,-5,-10,-15, and-20 torr) and passive leg elevation (LE, 50 cm) combined with lower body positive pressure (LBPP,+ 5,+ 10, and+ 20 torr) were utilized to elicit central hypovolemia and hypervolemia, respectively. Range of CVP (from LBNP to LE+ LBPP) was similar in the AF (from-3.9 to+ 1.9 mm Hg) and HF (from-4.0 to+ 2.2 mm Hg). However, FVR/CVP was significantly less in the HF (-1.8+/-0.1 unit. mm Hg-1) than AF (-34+/-0.1 unit. mm Hg-1). The FVR decrease in response to increase in CVP was significantly diminished in the HF (-1.46+/-0.45 unit. mm Hg-1) compared to the AF (-4.40+/-0.97 unit. mm Hg-1), and during LBNP induced unloading the FVR/CVP of the HF (-2.01+/-0.49 unit. mm Hg-1) was less (P< 0.08) than the AF (-3.28+/-0.69 unit. mm Hg-1). We concluded that the cardiopulmonary baroreceptor mediated FVR reflex response was significantly less sensitive to changes in CVP in individuals who practice exercise training.
DOI: --
发表时间: 1988
期刊: HYPERTENSION
影响因子: 8.3
作者:
G. Grassi;J. Cléroux;C. Cuspidi;L. Sampieri;G. Bolla;G. Mancia
通讯作者: G. Mancia
有氧健身:I. 容量调节激素对低头倾斜的反应。
DOI: --
发表时间: 1992
影响因子: 4.1
作者:
Shi,X;Squires,WG;Williamson,JW;Crandall,CG;Chen,JJ;Krock,LP;Raven,PB
通讯作者: Raven,PB
急性血容量扩张后心肺压力反射控制前臂血管阻力。
DOI: --
发表时间: 1991
期刊: Aviation, space, and environmental medicine
影响因子: --
作者:
Mack,GW;Quigley,BM;Nishiyasu,T;Shi,X;Nadel,ER
通讯作者: Nadel,ER
慢性耐力运动训练:血压调节不足和对 LBNP 耐受性降低的情况。
DOI: --
发表时间: 1993
影响因子: 4.1
作者:
Raven,PB;Pawelczyk,JA
通讯作者: Pawelczyk,JA
高血压刺激期间主动脉压力反射对心率的控制:健身的效果。
DOI: 10.1152/jappl.1993.74.4.1555
发表时间: 1993
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Shi,X;Andresen,JM;Potts,JT;Foresman,BH;Stern,SA;Raven,PB
通讯作者: Raven,PB