EPIDERMAL THICKNESS AND BIOMECHANICAL PROPERTIES OF PLANTAR TISSUES IN DIABETIC FOOT
EPIDERMAL THICKNESS AND BIOMECHANICAL PROPERTIES OF PLANTAR TISSUES IN DIABETIC FOOT
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DOI：
10.1016/j.ultrasmedbio.2011.04.004
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发表时间：
2011-07-01
影响因子：
2.9
通讯作者：
Cheing, Gladys L. Y.
中科院分区：
文献类型：
--
作者：
Chao, Clare Y. L.;Zheng, Yong-Ping;Cheing, Gladys L. Y.
糖尿病足是糖尿病患者的常见并发症，但尚不清楚这种变化是从皮肤表面还是足底组织下面开始的。本研究比较了糖尿病合并或不合并并发症患者的表皮厚度和总足底软组织的厚度和硬度。72名糖尿病患者，包括22名神经病变患者，16名足部溃疡患者，34名无并发症的纯糖尿病患者和40名健康对照者参加了这项研究。使用高频超声检查足底皮肤的表皮层的厚度;使用组织超声触诊系统测量大脚趾、第一、第三和第五跖骨头以及足跟垫的总足底软组织的厚度和刚度。与对照组相比，糖尿病足溃疡患者的足底皮肤平均表皮厚度减少了15%，神经病变患者减少了9%，而单纯糖尿病患者增加了6%。在3个糖尿病组中，除第一跖骨头外，所有测试部位的足底软组织总厚度均增加8%（所有p < 0.05）。与对照组相比，所有糖尿病组的足底软组织硬度在所有测试部位均增加（所有p < 0.05）。在糖尿病患者中，特别是在患有神经病变或溃疡的人中，足底表皮皮肤变得更薄并且足底软组织萎缩，这增加了组织破裂和溃疡形成的风险。（电子邮件：rsgladys@polyu.edu.hk）（C）2011年世界医学和生物学超声联合会。
Diabetic foot is a common complication for people with diabetes but it is unclear whether the change is initiated from the skin surface or underneath plantar tissues. This study compared the thickness of epidermis and the thickness and stiffness of the total plantar soft tissue among people with diabetes with or without complications. Seventy-two people with diabetes, including 22 people with neuropathies, 16 foot ulcerations, 34 pure diabetics without complications and 40 healthy controls participated in the study. The thickness of the epidermal layer of the plantar skin was examined using high-frequency ultrasonography; the thickness and stiffness of the total plantar soft tissue were measured by using tissue ultrasound palpation system at the big toe, the first, third and fifth metatarsal heads; and the heel pad. Compared with the control group, the average epidermal thickness of plantar skin was reduced by 15% in people with diabetic foot ulceration and 9% in people with neuropathy, but was increased by 6% in pure diabetics. There was an 8% increase in total thickness of plantar soft tissue in the 3 diabetic groups at all testing sites (all p < 0.05), except the first metatarsal head. The stiffness of plantar soft tissue was increased in all diabetic groups at all testing sites compared with the control (all p < 0.05). The epidermal plantar skin becomes thinner and plantar soft tissues stiffen in people with diabetes, particularly in persons who have neuropathy or ulceration, which increases the risk of tissue breakdown and ulceration formation. (E-mail: rsgladys@polyu.edu.hk) (C) 2011 World Federation for Ultrasound in Medicine & Biology.