LocustDB: a relational database for the transcriptome and biology of the migratory locust (Locusta migratoria).
LocustDB: a relational database for the transcriptome and biology of the migratory locust (Locusta migratoria).
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LocustDB：迁徙蝗虫（colcusta偏偏）转录组和生物学的关系数据库。
DOI：
10.1186/1471-2164-7-11
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发表时间：
2006-01-21
期刊：
影响因子：
4.4
通讯作者：
Kang, Le
中科院分区：
文献类型：
--
作者：
Ma, Zongyuan;Yu, Jun;Kang, Le
飞蝗（Locusta migratoria）是直翅目害虫，也是半代谢昆虫生物学研究的代表成员。它的转录组数据为分子昆虫学提供了宝贵的信息，并为其他医学，农学和生态学相关昆虫的比较研究铺平了道路。我们开发了蝗虫的第一个转录组数据库（LocustDB），建立必要的基础设施，以整合，组织和检索数据，无论是目前可用的或在未来获得。LocustDB目前拥有来自蝗虫的45，474个高质量EST序列，这些序列被组装成12，161个unigenes。它通过用户友好的网络界面，允许研究人员自由访问序列数据，包括同源/正向序列，功能注释和途径分析，基于保守的正向序列组（COG），基因本体（GO），蛋白质结构域（InterPro）和功能途径（KEGG）。它还提供了根据飞蝗和其他五种无脊椎动物物种，包括蚕、蜜蜂、果蝇、蚊子和线虫的数据进行比较分析的资料。LocustDB的网址是。LocustDB从直翅目和半变态昆虫的第一个转录组信息开始，并将扩展到提供一个框架，用于整合相关昆虫群体的基因组数据和跨物种比较研究的工作台。
The migratory locust (Locusta migratoria) is an orthopteran pest and a representative member of hemimetabolous insects for biological studies. Its transcriptomic data provide invaluable information for molecular entomology and pave a way for the comparative research of other medically, agronomically, and ecologically relevant insects. We developed the first transcriptomic database of the locust (LocustDB), building necessary infrastructures to integrate, organize, and retrieve data that are either currently available or to be acquired in the future. LocustDB currently hosts 45,474 high-quality EST sequences from the locust, which were assembled into 12,161 unigenes. It, through user-friendly web interfaces, allows investigators to freely access sequence data, including homologous/orthologous sequences, functional annotations, and pathway analysis, based on conserved orthologous groups (COG), gene ontology (GO), protein domain (InterPro), and functional pathways (KEGG). It also provides information from comparative analysis based on data from the migratory locust and five other invertebrate species, including the silkworm, the honeybee, the fruitfly, the mosquito and the nematode. The website address of LocustDB is . LocustDB starts with the first transcriptome information for an orthopteran and hemimetabolous insect and will be extended to provide a framework for incorporating in-coming genomic data of relevant insect groups and a workbench for cross-species comparative studies.