Dietary Effects on Pain Symptoms in Patients with Fibromyalgia Syndrome: Systematic Review and Future Directions.
Dietary Effects on Pain Symptoms in Patients with Fibromyalgia Syndrome: Systematic Review and Future Directions.
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DOI：
10.3390/nu15030716
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发表时间：
2023-01-31
期刊：
影响因子：
5.9
通讯作者：
Takata Y
中科院分区：
文献类型：
--
作者：
Maddox EK;Massoni SC;Hoffart CM;Takata Y
纤维肌痛综合征（FMS）是公认的，其诊断困难，其主观病理学。目前既没有已知的治愈方法，也没有推荐的治疗饮食来帮助多学科治疗。我们进行了一项系统性综述，以调查饮食是否可以改善纤维肌痛的疼痛症状。通过2022年3月的PubMed检索，识别出126篇摘要。我们纳入了FMS患者饮食和疼痛症状的干预性和观察性研究。在筛选标题、摘要和全文后，选择了12项研究，包括11项干预性研究和1项观察性研究。这些研究包括546名参与者，并调查了植物性饮食（n = 3），抗炎饮食（n = 1），无麸质饮食（n = 2）和消除/限制饮食（n = 6）。这些研究通过疼痛视觉模拟量表、纤维肌痛影响问卷/修订的纤维肌痛影响问卷、压痛点计数、疼痛压力阈值和/或总肌痛评分评估疼痛症状。九项研究，包括所有三项植物性饮食研究，报告了各自饮食对疼痛症状测量的统计学显著有益影响。鉴于纳入研究的样本量小且干预持续时间短，目前存在有限的证据向FMS患者推荐任何特定的饮食。进一步的研究是必要的，以澄清具体的饮食建议和探索其潜在的机制。
Fibromyalgia syndrome (FMS) is recognized for its difficulty to diagnose and its subjective symptomatology. There is neither a known cure nor a recommended therapeutic diet to aid in the multidisciplinary treatment. We conducted a systematic review to investigate if diets can improve pain symptoms of fibromyalgia. Through the PubMed search in March 2022, 126 abstracts were identified. We included both intervention and observational studies of diets and pain symptoms among patients with FMS. After screening titles, abstracts, and full-texts, 12 studies, including 11 intervention and one observational study, were selected. These studies included 546 participants and investigated plant-based diets (n = 3), anti-inflammatory diets (n = 1), gluten-free diets (n = 2), and elimination/restrictive diets (n = 6). These studies assessed pain symptoms through visual analogue scale for pain, fibromyalgia impact questionnaire/revised fibromyalgia impact questionnaire, tender point count, pain pressure threshold, and/or total myalgic score. Nine studies, including all three plant-based diet studies, reported statistically significant beneficial effects of their respective diets on pain symptom measurements. Given the small sample size and short intervention duration of the included studies, limited evidence currently exists to recommend any specific diet to patients with FMS. Further research is warranted to clarify specific diets to recommend and explore their potential mechanisms.