Fusel Alcohols Regulate Translation Initiation by Inhibiting eIF2B to Reduce Ternary Complex in a Mechanism That May Involve Altering the Integrity and Dynamics of the eIF2B Body
Fusel Alcohols Regulate Translation Initiation by Inhibiting eIF2B to Reduce Ternary Complex in a Mechanism That May Involve Altering the Integrity and Dynamics of the eIF2B Body
复制标题
杂醇醇通过抑制 eIF2B 减少三元复合物来调节翻译起始,其机制可能涉及改变 eIF2B 体的完整性和动态
DOI:
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发表时间:
2010
影响因子:
3.3
通讯作者:
M. Ashe
中科院分区:
文献类型:
--
作者:
Eleanor Taylor;S. Campbell;Christian D. Griffiths;P. Reid;John W. Slaven;Richard J Harrison;Paul F. G. Sims;G. Pavitt;D. Delneri;M. Ashe
This study highlights a connection between the eIF2B body and the regulation of translation initiation as a response to stress in Saccharomyces cerevisiae. Fusel alcohols are involved in signaling nitrogen scarcity to the cell and they inhibit protein synthesis by preventing the movement of the eIF2B body throughout the cell.
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影响因子:
10.5
作者:
Cherkasova, VA;Hinnebusch, AG
通讯作者:
Hinnebusch, AG
DOI:
--
发表时间:
1999
期刊:
Alcoholism, clinical and experimental research.
影响因子:
--
作者:
Stubbs,CD;Slater,SJ
通讯作者:
Slater,SJ
影响因子:
3.3
作者:
LaValle,R;Wittenberg,C
通讯作者:
Wittenberg,C
影响因子:
3.3
作者:
Cutler, NS;Pan, XW;Cardenas, ME
通讯作者:
Cardenas, ME
影响因子:
10.5
作者:
Pavitt, GD;Ramaiah, KVA;Hinnebusch, AG
通讯作者:
Hinnebusch, AG