The vertebrate genome annotation (Vega) database

The vertebrate genome annotation (Vega) database
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DOI:
10.1093/nar/gkm987
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发表时间:
2008-01-01
影响因子:
14.9
通讯作者:
Harrow, J. L.
Harrow, J. L.
中科院分区:
生物学2区
文献类型:
--
作者:
Wilming, L. G.;Gilbert, J. G. R.;Harrow, J. L.

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脊椎动物基因组注释(VEGA)数据库(http://vega.sanger.ac.uk)于2004年首次公开,旨在查看在Wellcome Sanger Sanger Institute上产生的人,鼠标和斑马鱼基因组序列的手动注释。自初次发布以来,人类注释的基因座的数量已翻了一番,达到33 000,现在包含24个人类染色体中的20个,四个全小鼠染色体和斑马鱼Danio rerio rerio基因组的全面注释。此外,我们还提供了小鼠和人类的许多单倍型区域的手动注释,以及在Vega独有的猪和狗中具有比较感兴趣的区域。
The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) was first made public in 2004 and has been designed to view manual annotation of human, mouse and zebrafish genomic sequences produced at the Wellcome Trust Sanger Institute. Since its initial release, the number of human annotated loci has more than doubled to close to 33 000 and now contains comprehensive annotation on 20 of the 24 human chromosomes, four whole mouse chromosomes and around 40 of the zebrafish Danio rerio genome. In addition, we offer manual annotation of a number of haplotype regions in mouse and human and regions of comparative interest in pig and dog that are unique to Vega.