Smoking and comorbidities are associated with COVID-19 severity and mortality in 565 patients treated in Turkey: a retrospective observational study
Smoking and comorbidities are associated with COVID-19 severity and mortality in 565 patients treated in Turkey: a retrospective observational study
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DOI：
10.1590/1806-9282.66.12.1679
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发表时间：
2020-12-01
期刊：
影响因子：
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通讯作者：
Saylan, Bengu
中科院分区：
文献类型：
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作者：
Caliskan, Tayfun;Saylan, Bengu
目的：目的：探讨2019冠状病毒病（COVID-19）住院患者的吸烟率和合并症的患病率，并评估其与疾病严重程度和死亡率的关系。方法：将2019冠状病毒病住院患者分为门诊组、重症监护组（ICU）、存活组和死亡组。非COVID-19患者作为对照组。结果：在吸烟、哮喘、糖尿病、痴呆、冠状动脉疾病（CAD）、高血压、慢性肾功能衰竭和心律失常方面，COVID-19患者与非COVID-19患者之间无差异（p> 0. 05）。年龄较大（比值比（OR），7.061; 95%置信区间（CI）：1.041-1.082; p< 0.0001）、慢性阻塞性肺疾病（COPD）（OR，2.775; 95% CI：1.128-6.829; p=0.026）和CAD（OR，2.696; 95% CI：1.216-5.974; p=0.015）与入住ICU显著相关。目前吸烟（OR，5.101; 95%CI：2.382-10.927; p
OBJECTIVE: We aimed to explore the prevalence of smoking rates and comorbidities and evaluate the relationship between them and disease severity and mortality in inpatients with COVID-19.METHODS: COVID-19 patients were divided into the following groups: clinic group, intensive care unit (ICU) group, survivors, and non-survivors. Non-COVID-19 patients were included as a control group. The groups were compared.RESULTS: There was no difference between patients with and without COVID-19 in terms of smoking, asthma, diabetes, dementia, coronary artery disease (CAD), hypertension, chronic renal failure and arrhythmia (p>0.05). Older age (Odds ratio (OR), 7.061; 95% confidence interval (CI):1.041-1.082; p< 0.0001), chronic obstructive pulmonary disease (COPD) (OR, 2.775; 95% 0:1.128-6.829; p=0.026) and CAD (OR, 2.696; 95% CI: 1.216-5.974; p=0.015) were significantly associated with ICU admission. Current smoking (OR, 5.101; 95% CI: 2.382-10.927; p