The Public Health Impact of Coccidioidomycosis in Arizona and California
The Public Health Impact of Coccidioidomycosis in Arizona and California
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DOI：
10.3390/ijerph8041150
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发表时间：
2011-04-01
影响因子：
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通讯作者：
Galgiani, John N.
中科院分区：
文献类型：
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作者：
Hector, Richard F.;Rutherford, George W.;Galgiani, John N.
过去十年中，亚利桑那州和加利福尼亚州报告的球孢子菌病病例数急剧增加，从 2001 年到 2006 年，这两个州的发病率分别增加了 97.8% 和 91.1%。在那些报告了种族/民族信息的病例中，与其他种族/族裔群体相比，亚利桑那州的黑人/非裔美国人、加利福尼亚州的西班牙裔和非洲裔/美国人的患病频率要高得多。缺乏早期诊断仍然是一个问题，特别是在可疑的社区获得性肺炎中，这凸显了需要更快速、更灵敏的检测。同样，目前可用的治疗方法无法减少这种疾病的持续时间和发病率，这凸显了对改进的治疗方法和预防性疫苗的需要。
The numbers of reported cases of coccidioidomycosis in Arizona and California have risen dramatically over the past decade, with a 97.8% and 91.1% increase in incidence rates from 2001 to 2006 in the two states, respectively. Of those cases with reported race/ethnicity information, Black/African Americans in Arizona and Hispanics and African/Americans in California experienced a disproportionately higher frequency of disease compared to other racial/ethnic groups. Lack of early diagnosis continues to be a problem, particularly in suspect community-acquired pneumonia, underscoring the need for more rapid and sensitive tests. Similarly, the inability of currently available therapeutics to reduce the duration and morbidity of this disease underscores the need for improved therapeutics and a preventive vaccine.