Chromatographic characterization of macroporous monolithic silica prepared via sol-gel process
Chromatographic characterization of macroporous monolithic silica prepared via sol-gel process
复制标题
溶胶-凝胶法制备大孔整体二氧化硅的色谱表征
DOI：
10.1016/s0927-7757(01)00642-2
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
N. Tanaka
中科院分区：
文献类型：
--
作者：
N. Ishizuka;H. Minakuchi;K. Nakanishi;K. Hirao;N. Tanaka
采用溶胶凝胶法制备了具有相分离功能的连续多孔二氧化硅整体柱，并在碱性溶剂中利用尿素的水解反应制备了可用于层析的扩展介孔结构。湿凝胶骨架与外部溶剂界面处的溶解-再沉淀动力学影响骨架内形成的孔的大小和体积。在200℃以上，其孔径达到了大孔尺寸(>；50 nm)。层析结果表明，与填充5μm硅胶颗粒的常规色谱柱相比，具有较宽中孔的整体硅胶色谱柱可以缩短分离时间。
A continuous porous silica monolith prepared by the sol-gel process including phase separation was aged in a basic solvent making use of hydrolysis of urea to prepare extended mesopore structures for chromatographic applications. The dissolution–reprecipitation kinetics at the interfaces between wet gel skeletons and an external solvent affected the size and volume of pores formed within the skeletons. At above 200°C, the pore size attained the macropore dimensions (>50 nm). The results of chromatography indicate that the monolithic silica column with wide mesopore could reduce the separation time compared to the conventional column packed with 5 μm silica particle.
影响因子：
7.4
作者：
MacNair, JE;Patel, KD;Jorgenson, JW
通讯作者：
Jorgenson, JW