Recent Developments in the Nitroxide-Catalyzed Oxidation of Amines: Preparation of Imines and Nitriles
Recent Developments in the Nitroxide-Catalyzed Oxidation of Amines: Preparation of Imines and Nitriles
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DOI：
10.1002/cctc.201600858
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发表时间：
2016-11-22
期刊：
影响因子：
4.5
通讯作者：
Bailey, William F.
中科院分区：
文献类型：
--
作者：
Bartelson, Ashley L.;Lambert, Kyle M.;Bailey, William F.
本概念着重介绍了克里思（2，2，6，6-四甲基哌啶基-N-氧基）催化胺氧化反应及相关催化体系的发现和发展。这些系统的最重要的特征是，在反应介质中进行轻微的修改，胺被选择性地氧化为亚胺或腈。讨论了各种苄基胺、烯丙基胺和脂肪胺的氧化反应，以及可能的反应机理途径。
This Concept highlights the discovery and developments in the oxidations of amines catalyzed by TEMPO (2,2,6,6-tetramethylpiperidinyl- N-oxyl) and related catalytic systems. The most important feature of these systems is that, with slight modifications in the reaction media, amines are selectively oxidized to either an imine or nitrile. Progress made toward the oxidation of various benzylic, allylic, and aliphatic amines, and possible reaction mechanism pathways are discussed.