Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain
Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain
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DOI：
10.1016/j.jpain.2004.10.005
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发表时间：
2005-01-01
期刊：
影响因子：
4
通讯作者：
Gollub, RL
中科院分区：
文献类型：
--
作者：
Kong, J;Fufa, DT;Gollub, RL
在这项初步研究中，我们在一组健康受试者中比较了三种针灸模式——手动、电针和安慰剂（使用Streitberger安慰剂针）的镇痛效果，我们发现verum针灸治疗，而不是安慰剂，降低了对校准的有害热刺激的疼痛评分。这一发现主要是由于完成5期研究的11名受试者中有5名具有高度显著的镇痛作用。在5名应答者中，2名仅对电针有应答，3名仅对手针有应答，提示针刺对实验性疼痛的镇痛作用可能依赖于受试者和方式。我们开发了一个简单的定量评估工具，主观针灸。感觉量表（SASS），由9个描述词和一个焦虑量表组成，研究针刺引起的德气感觉与针刺治疗效果的关系。SASS结果证实，deqi感觉是复杂的，所有受试者在每个模式下都对多个描述符进行评级。我们发现镇痛与麻木和疼痛的SASS评分有显著相关性，但与刺痛、悸动、刺痛、灼烧、沉重、丰满或疼痛评分无显著相关性。提示德气感觉的属性可作为有效治疗的临床指标。观点：本研究结果表明，针刺镇痛作用存在受试者个体差异和针刺方式差异。这表明转换针灸模式可能是治疗无反应患者的一种选择。(C) 2005年由美国疼痛学会出版。
In this pilot study comparing the analgesic effects of three acupuncture modes-manual, electro, and placebo (with Streitberger placebo needles)-in a cohort of healthy subjects, we found that verum acupuncture treatment, but not placebo, lowered pain ratings in response to calibrated noxious thermal stimuli. This finding was mainly the result of highly significant analgesia in 5 of the 11 subjects who completed the 5-session study. Of the 5 responders, 2 responded only to electroacupuncture and 3 only to manual acupuncture, suggesting that acupuncture's analgesic effects on experimental pain may be dependent on both subject and mode. We developed a simple quantitative assessment tool, the Subjective Acupuncture. Sensation Scale (SASS), comprised of 9 descriptors and an anxiety measure to study the relationship between the deqi sensation induced by acupuncture and the putative therapeutic effects of acupuncture. The SASS results confirm that the deqi sensation is complex, with all subjects rating multiple descriptors during each mode. We found significant correlations of analgesia with SASS ratings of numbness and soreness, but not with ratings of stabbing, throbbing, tingling, burning, heaviness, fullness, or aching. This suggests that attributes of the deqi sensation may be useful clinical indicators of effective treatment.Perspective: The results of this study indicate the existence of both individual subject and acupuncture mode variability in the analgesic effects of acupuncture. This suggests that switching acupuncture mode may be a treatment option for unresponsive patients. (C) 2005 by the American Pain Society.