CIRCADIAN SYMPTOM FLUCTUATIONS IN PEOPLE WITH ANXIETY DISORDERS
CIRCADIAN SYMPTOM FLUCTUATIONS IN PEOPLE WITH ANXIETY DISORDERS
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DOI：
10.1016/0165-0327(86)90072-8
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发表时间：
1986-11-01
影响因子：
6.6
通讯作者：
MCPHEE, KM
中科院分区：
文献类型：
--
作者：
CAMERON, OG;LEE, MA;MCPHEE, KM
昼夜节律异常已在抑郁症患者中得到证实，包括早晨症状最严重的趋势。虽然一些研究表明，焦虑症患者的症状在一天的晚些时候会更严重，但没有详细的研究报告。在86例焦虑症患者（63例惊恐障碍或广场恐怖症伴惊恐发作）中，焦虑症状在下午或晚上比早上更严重，心率或口腔温度无异常。这是第一次系统地证明了除抑郁症外的任何疾病的昼夜情绪波动。
Circadian rhythm abnormalities have been demonstrated in people with depression, including a tendency toward maximal symptom severity in the morning. Although a few studies have suggested that symptoms in people with anxiety are worse later in the day, no detailed study of this observation has been reported. In 86 patients with anxiety disorders (63 with panic disorder or agoraphobia with panic attacks), anxiety symptoms tended to be more severe in the afternoon or evening than in the morning, with no abnormalities of heart rate or oral temperature. This is the first systematic demonstration of a circadian fluctuation of mood in any disorder other than depression.