ARABIDOPSIS ABA RESPONSE GENE ABI1 - FEATURES OF A CALCIUM-MODULATED PROTEIN PHOSPHATASE
ARABIDOPSIS ABA RESPONSE GENE ABI1 - FEATURES OF A CALCIUM-MODULATED PROTEIN PHOSPHATASE
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DOI：
10.1126/science.7910981
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发表时间：
1994-06-03
期刊：
影响因子：
56.9
通讯作者：
GIRAUDAT, J
中科院分区：
文献类型：
--
作者：
LEUNG, J;BOUVIERDURAND, M;GIRAUDAT, J
拟南芥ABI 1基因座是植物发育过程中广泛的脱落酸（阿坝）反应所必需的。在这里，ABI 1被证明可以调节叶片的气孔开度和根分生组织的有丝分裂活动。ABI 1基因被克隆并预测编码一个信号蛋白。虽然其羧基末端结构域与丝氨酸-苏氨酸磷酸酶2C相关，但ABI 1蛋白具有独特的氨基末端延伸，其含有EF手型钙结合位点。这些结果表明，ABI 1蛋白是一个Ca 2+调节的磷酸酶和功能整合阿坝和Ca 2+信号与磷酸化依赖的反应途径。
The Arabidopsis ABI1 locus is essential for a wide spectrum of abscisic acid (ABA) responses throughout plant development. Here, ABI1 was shown to regulate stomatal aperture in leaves and mitotic activity in root meristems. The ABI1 gene was cloned and predicted to encode a signaling protein. Although its carboxyl-terminal domain is related to serine-threonine phosphatase 2C, the ABI1 protein has a unique amino-terminal extension containing an EF hand calcium-binding site. These results suggest that the ABI1 protein is a Ca2+-modulated phosphatase and functions to integrate ABA and Ca2+ signals with phosphorylation-dependent response pathways.