Tone of canine ileocolonic junction: topography and response to phasic contractions.
Tone of canine ileocolonic junction: topography and response to phasic contractions.
复制标题
犬回结肠交界处的音调：地形和对阶段性收缩的反应。
DOI：
10.1152/ajpgi.1985.249.3.g350
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Dent,J
中科院分区：
文献类型：
--
作者：
Quigley,EM;Phillips,SF;Cranley,B;Taylor,BM;Dent,J
我们希望定义犬回结肠括约肌（ICS）的生理学，并检查与该区域解剖结构相关的功能。从7只具有孤立回结肠袢的犬中进行ICS时的张力延长记录，并评估回肠和结肠扩张对括约肌张力的影响。在急性实验中，在ICS处测量牵拉压力，并且高压区的位置与该区域的解剖结构相关。ICS时的基础张力约为30 cmH 2 O;结肠和回肠扩张增强了张力。高压区始终以解剖ICS为中心，但其延伸到邻近回肠和结肠，总长度为2.0 cm（范围1.5-3.0 cm）。阶段性收缩有助于维持紧张度在ICS，和协调模式的阶段性收缩似乎有助于该地区的括约肌属性。
We wished to define the physiology of the canine ileocolonic sphincter (ICS) and to examine function in relation to the region's anatomy. Prolonged recordings of tone at the ICS were made from seven dogs with isolated ileocolonic loops, and the effects of ileal and colonic distension on sphincteric tone were assessed. In acute experiments, pull-through pressures were measured at the ICS, and the location of the high-pressure zone was related to the region's anatomy. Basal tone at the ICS of approximately 30 cmH2O was confirmed; tone was augmented by colonic and ileal distension. The high-pressure zone was always centered on the anatomic ICS, but it extended into the adjacent ileum and colon for a total length of 2.0 cm (range 1.5–3.0 cm). Phasic contractions contributed to the maintenance of tone at the ICS, and a coordinated pattern of phasic contractions appears to contribute to the sphincteric properties of the region.