Asymmetric total synthesis of (+)-fostriecin.
Asymmetric total synthesis of (+)-fostriecin.
复制标题
( )-磷霉素的不对称全合成。
DOI：
10.1021/ol025537r
复制
发表时间：
2002
期刊：
影响因子：
5.2
通讯作者：
Falck,JR
中科院分区：
文献类型：
--
作者：
Reddy,YKrishna;Falck,JR
The title compound, a potent protein phosphatase inhibitor and anticancer agent, was prepared by an efficient, multiconvergent asymmetric synthesis. Key transformations include a ring forming olefin metathesis leading to the α,β-unsaturated lactone and creation of the triene moiety via Suzuki cross-coupling.
