Research Funding of the Top Science Gaps in the American Heart Association Cardiac Arrest Guidelines.
Research Funding of the Top Science Gaps in the American Heart Association Cardiac Arrest Guidelines.
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美国心脏协会心脏骤停指南中顶尖科学差距的研究资助。
DOI：
10.1161/circoutcomes.120.007627
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Kurz,MichaelC
中科院分区：
文献类型：
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作者：
Coute,RyanA;Panchal,AshishR;Mader,TimothyJ;Kurz,MichaelC
循环血管质量结局。2021; 14：e007627. DOI：10.1161/CIRCOUTCOMES. 120.007627 May 2021 657摘要，以及Panchal等人6发表的知识差距定义/理由。该分析利用了公开的资助信息，因此不需要机构审查委员会的批准。这些数据可供任何研究人员用于复制结果的目的。搜索产生了1518个NIH资助的赠款，其中172个（11.3%）被归类为个人CA赠款。共有42个（24.4%）没有解决前10大科学差距。剩余的130笔赠款用于解决以下科学差距：（78赠款; 45.3%），预测CA患者的风险（12; 7%），开发早期神经预测工具（7; 4.1%），血流动力学监测/目标导向复苏（4; 2.3%），优化提供者的教育策略（4; 2.3%），最佳气道策略（2; 1.2%），以及了解旁观者为什么没有反应（1; 0.6%）。先前存在的科学网络或数据中心占19项（11%）赠款，3项（1.7%）赠款解决了> 1个科学差距。公认的科学差距，在调度定向心肺复苏，个性化复苏策略，并为院外CA识别和响应的新技术没有收到专门针对NIH赠款资金。在研究期间，年度资金从4010万美元增加到4210万美元。
Circ Cardiovasc Qual Outcomes. 2021; 14: e007627. DOI: 10.1161/CIRCOUTCOMES. 120.007627 May 2021 657 abstract, and the knowledge gap definition/rationale published by Panchal et al. 6 This analysis utilized publicly available grant information and, therefore, did not require institutional review board approval. The data are available to any researcher for the purposes of reproducing the results.The search yielded 1518 NIH-funded grants, of which 172 (11.3%) were classified as individual CA grants. A total of 42 (24.4%) did not address a top 10 scientific gap. The remaining 130 grants addressed the following scientific gaps: optimization of post-CA care (78 grants; 45.3%), prediction of patients at risk of CA (12; 7%), developing tools for early neuroprognostication (7; 4.1%), hemodynamic monitoring/goal-directed resuscitation (4; 2.3%), optimizing educational strategies for providers (4; 2.3%), optimal airway strategies (2; 1.2%), and understanding why bystanders fail to respond (1; 0.6%). Previously existing scientific networks or data centers accounted for 19 (11%) grants, and 3 (1.7%) grants addressed> 1 science gap. Recognized scientific gaps in dispatchdirected cardiopulmonary resuscitation, individualized resuscitation strategies, and novel technology for outof-hospital CA identification and response did not receive specifically directed NIH grant funding. Annual funding increased from $40.1 M to $42.1 M over the study period.