Physical and psychosocial outcome for young adults with treated malignancy
Physical and psychosocial outcome for young adults with treated malignancy
复制标题
DOI：
10.3109/08880019709009492
复制
发表时间：
1997-05-01
影响因子：
1.7
通讯作者：
Lanning, M
中科院分区：
文献类型：
--
作者：
Kokkonen, J;Vainionpaa, L;Lanning, M
我们重新检查了一组27名（10名女性，17名男性）年龄在16-26岁之间的患者的身体，神经，神经心理，社会和精神状况，这些患者在儿童时期曾患有恶性疾病。20名幸存者患有白血病，其余的患有不同的实体瘤。只有三分之一（31%）的受试者被认为没有任何临床显著的身体健康问题或功能症状，肌肉骨骼和内分泌疾病是最常见的。在神经心理测试面板，包括语言和操作智商的幸存者有显着较低的分数。早期发病和接受放射治疗与受损的测试结果最显着相关，特别是记忆功能。五分之一的幸存者报告说，他们患有阅读和写作问题，这影响了他们在学校的成功，研究组的受试者比对照组的受试者更少进入高中。社会指数表明性发育迟缓和与父母分离。在一个一次性的采访中出现的明显的精神问题是相同的，在控制组。总之，高达三分之二的儿童癌症幸存者作为年轻的成年人仍然有身体或神经心理健康问题，一半表现出延迟的性心理成熟。各种疾病的严重程度表明，对这一小群人进行了长期但以个人为导向的随访，并有机会对他们的主要问题进行身体，社会或心理管理。
We reexamined the physical, neurological, neuropsychological, social, and psychiatric circumstances of a group of 27 (10 females, 17 males) patients at the ages of 16-26 years who had survived a malignant disease during childhood. Twenty survivors had had leukemia and the rest different solid tumors. Only a third (31%) of the subjects were considered to be without any clinically significant physical health problems or functional symptoms, musculoskeletal and endocrinological disorders being the most common. In the neuropsychological test panel including verbal and performance IQ the survivors had significantly lower scores. Early onset of the disease and receiving radiotherapy correlated with impaired test results most significantly, especially on memory functions. One in five of the survivors reported having suffered from reading and writing problems that interfered with success in school and the subjects of the study group had progressed to high school less often than control subjects. The social indices indicated delayed development of sexuality and separation from parents. Overt mental problems appearing at a one-off interview were the same as in the control group. In conclusion, up to two thirds of the childhood cancer survivors as young adults still have physical or neuropsychological health problems and half showed delayed psychosexual maturation. This magnitude of various disorders Indicates a long-term but individually oriented follow-up Of this small group with the opportunity of physical, social, or psychological management of their main problem.