The influence of attention deficits on functional recovery post stroke during the first 12 months after discharge from hospital
The influence of attention deficits on functional recovery post stroke during the first 12 months after discharge from hospital
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DOI：
10.1136/jnnp.2007.125609
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发表时间：
2008-06-01
影响因子：
11
通讯作者：
Ashburn, A.
中科院分区：
文献类型：
--
作者：
Hyndman, D.;Pickering, R. M.;Ashburn, A.
背景：注意缺陷与中风后恢复不良有关，并可能预测预后。目的探讨注意力对脑卒中患者出院后12个月内功能恢复的影响。方法：脑卒中患者在出院时、6个月和12个月后分别完成注意力、平衡、活动能力和日常生活活动能力的测量。我们使用相关分析和逐步线性回归来探索结果的潜在预测因素。结果：我们招募了122名男女，平均年龄70岁。出院时，分离注意缺陷56例（51%），持续注意缺陷45例（37%），听觉选择性注意缺陷43例（36%），视觉选择性注意缺陷41例（37%）。出院时的注意力与12个月后的活动能力、平衡能力和ADL结果相关。在控制出院时的结果水平后，12种关系中只有5种相关性仍然显著。逐步线性回归显示，出院时测量的结果，出院前的天数和药物数量是更好的预测结果：在任何情况下，出院时的注意变量都不能作为12个月结果的预测因子。结论：虽然注意与功能显著相关，但在控制出院时的功能能力后，这种相关性降低。此外，病变侧面和注意力变量并没有被证明是12个月后预后的重要预测因素。
Background: Attention deficits have been linked to poor recovery after stroke and may predict outcome. We explored the influence of attention on functional recovery post stroke in the first 12 months after discharge from hospital.Methods: People with stroke completed measures of attention, balance, mobility and activities of daily living (ADL) ability at the point of discharge from hospital, and 6 and 12 months later. We used correlational analysis and stepwise linear regression to explore potential predictors of outcome.Results: We recruited 122 men and women, mean age 70 years. At discharge, 56 (51%) had deficits of divided attention, 45 (37%) of sustained attention, 43 (36%) of auditory selective attention and 41 (37%) had visual selective attention deficits. Attention at discharge correlated with mobility, balance and ADL outcomes 12 months later. After controlling for the level of the outcome at discharge, correlations remained significant in only five of the 12 relationships. Stepwise linear regression revealed that the outcome measured at discharge, days until discharge and number of medications were better predictors of outcome: in no case was an attention variable at discharge selected as a predictor of outcome at 12 months.Conclusions: Although attention and function correlated significantly, this correlation was reduced after controlling for functional ability at discharge. Furthermore, side of lesion and the attention variables were not demonstrated as important predictors of outcome 12 months later.